Three-dimensional (3D) in vitro cell culture in natural hydrogels has shown promising results
in tissue engineering and regenerative medicine as it mimics the native extracellular matrix …

Fibrin is the provisional matrix formed after injury, setting the trajectory for the subsequent
stages of wound healing. It is commonly used as a wound sealant and a natural hydrogel for …

Hydrogels are used for 3D in vitro assays and tissue engineering and regeneration
purposes. For a thorough interpretation of this technology, an integral biomechanical …

The coagulation cascade represents a sophisticated and highly choreographed series of
molecular events taking place in the blood with important clinical implications. One key …

Skin is the largest organ of the body. Its integrity plays a crucial role in maintaining
physiological homeostasis, protects against mechanical forces and infections, fluid …

Sufficient blood perfusion is essential for all tissues to guarantee nutrient-and gas exchange.
As many diseases are induced by the reduction of blood perfusion such that these tissues …

Introduction Fibrin scaffolds are often utilized to treat chronic wounds. The monomer
fibrinogen used to create such scaffolds is typically derived from adult human or porcine …

Autologous implantable scaffolds that induce vasculogenesis have shown great potential in
tissue regeneration; however, previous attempts mainly relied on cell‐laden hydrogel …

Fibrin, the prominent extracellular matrix in early wound tissue, is discussed to influence
immune cells and healing. The nature of fibrinogen/fibrin to form fibrillary networks is …

Fibrin has been used clinically for wound coverings, surgical glues, and cell delivery
because of its affordability, cytocompatibility, and ability to modulate angiogenesis and …