Chimeric antigen receptors (CARs) are widely used by T cells (CAR-T cells), natural killer
cells dendritic cells and macrophages, and they are of great importance in cellular …

The chimeric antigen receptor (CAR) plays a dynamic role in targeting tumour-associated
antigens in cancer cells. This novel therapeutic discovery combines fragments of …

The Chimeric antigen receptor (CAR)-T cell therapy has made inroads in treating
hematological malignancies. Nonetheless, there are still multiple hurdles in CAR-T cell …

Macrophages and neutrophils are the main components of the innate immune system and
play important roles in promoting angiogenesis, extracellular matrix remodeling, cancer cell …

Chimeric antigen receptor (CAR)-T cell therapy has been shown to be an effective treatment
for hematological tumors, but the treatment of solid tumors still lacks effectiveness. In the …

Chimeric antigen receptor (CAR) T-cell therapies have shown impressive results in patients
with hematological malignancies; however, little success has been achieved in the treatment …

T-cells expressing synthetic chimeric antigen receptors (CARs) have revolutionized immuno-
oncology and highlighted the use of adoptive cell transfer, for the treatment of cancer. The …

Cancer stem cells (CSCs), a group of tumour cells with stem cell characteristics, have the
ability of self‐renewal, multi‐lineage differentiation and tumour formation. Since CSCs are …

The advent of chimeric antigen receptor (CAR)-T cell immunotherapies has led to
breakthroughs in the treatment of hematological malignancies. However, their success in …

Methods for suppressing the host immune system over the long term and improving
transplantation tolerance remain a primary issue in organ transplantation. Cell therapy is an …