A single bolus of docosahexaenoic acid promotes neuroplastic changes in the innervation of spinal cord interneurons and motor neurons and improves functional …
Docosahexaenoic acid (DHA) is an ω-3 polyunsaturated fatty acid that is essential in brain
development and has structural and signaling roles. Acute DHA administration is …
development and has structural and signaling roles. Acute DHA administration is …
A single dose of docosahexaenoic acid increases the functional recovery promoted by rehabilitation after cervical spinal cord injury in the rat
Task-specific rehabilitation has been shown to promote functional recovery after acute
spinal cord injury (SCI). Recently, the omega-3 polyunsaturated fatty acid, docosahexaenoic …
spinal cord injury (SCI). Recently, the omega-3 polyunsaturated fatty acid, docosahexaenoic …
Docosahexaenoic acid pretreatment confers protection and functional improvements after acute spinal cord injury in adult rats
JD Figueroa, K Cordero, K Baldeosingh… - Journal of …, 2012 - liebertpub.com
Currently, few interventions have been shown to successfully limit the progression of
secondary damage events associated with the acute phase of spinal cord injury (SCI) …
secondary damage events associated with the acute phase of spinal cord injury (SCI) …
Docosahexaenoic acid prevents white matter damage after spinal cord injury
RE Ward, W Huang, OE Curran, JV Priestley… - Journal of …, 2010 - liebertpub.com
We have previously shown that the omega-3 fatty acid docosahexaenoic acid (DHA)
significantly improves several histological and behavioral measures after spinal cord injury …
significantly improves several histological and behavioral measures after spinal cord injury …
A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury
WL Huang, VR King, OE Curran, SC Dyall, RE Ward… - Brain, 2007 - academic.oup.com
Previous studies have shown that omega-3 polyunsaturated fatty acids such as α-linolenic
acid and docosahexaenoic acid (DHA) are neuroprotective in models of spinal cord injury …
acid and docosahexaenoic acid (DHA) are neuroprotective in models of spinal cord injury …
Improved outcome after spinal cord compression injury in mice treated with docosahexaenoic acid
SN Lim, W Huang, JCE Hall, AT Michael-Titus… - Experimental …, 2013 - Elsevier
In this study we have characterised the locomotor recovery, and temporal profile of cell loss,
in a novel thoracic compression spinal cord injury (SCI) in the mouse. We have also shown …
in a novel thoracic compression spinal cord injury (SCI) in the mouse. We have also shown …
[HTML][HTML] Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies
I Paterniti, D Impellizzeri, R Di Paola, E Esposito… - Journal of …, 2014 - Springer
Background Two families of polyunsaturated fatty acid (PUFA), omega-3 (ω-3) and omega-6
(ω-6), are required for physiological functions. The long chain ω-3 PUFAs, eicosapentaenoic …
(ω-6), are required for physiological functions. The long chain ω-3 PUFAs, eicosapentaenoic …
[HTML][HTML] Innovative mouse model mimicking human-like features of spinal cord injury: Efficacy of Docosahexaenoic acid on acute and chronic phases
S Marinelli, V Vacca, F De Angelis, L Pieroni, T Orsini… - Scientific reports, 2019 - nature.com
Traumatic spinal cord injury has dramatic consequences and a huge social impact. We
propose a new mouse model of spinal trauma that induces a complete paralysis of …
propose a new mouse model of spinal trauma that induces a complete paralysis of …
Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat
VR King, WL Huang, SC Dyall, OE Curran… - Journal of …, 2006 - Soc Neuroscience
Spinal cord injury (SCI) is a cause of major neurological disability, and no satisfactory
treatment is currently available. Evidence suggests that polyunsaturated fatty acids (PUFAs) …
treatment is currently available. Evidence suggests that polyunsaturated fatty acids (PUFAs) …
Docosahexaenoic acid reduces microglia phagocytic activity via miR-124 and induces neuroprotection in rodent models of spinal cord contusion injury
Microglia are activated after spinal cord injury (SCI), but their phagocytic mechanisms and
link to neuroprotection remain incompletely characterized. Docosahexaenoic acid (DHA) …
link to neuroprotection remain incompletely characterized. Docosahexaenoic acid (DHA) …
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