A series of new hybrid derivatives 1a–c, 2a–c, 3a–c, 4a–c, 5a–c, inspired by nature, were
synthesized and studied as multifunctional agents for the treatment of Alzheimer's disease …

By using fragments endowed with interesting and complementary properties for the
treatment of Alzheimer's disease (AD), a novel series of cinnamamide-dibenzylamine …

Alzheimer's disease (AD) is a complex neurodegenerative disease with multiple
pathological features. Multifunctional compounds able to simultaneously interact with …

Alzheimer disease (AD) is a complex and progressive neurodegenerative disease. AD is
one of the greatest challenges to modern medicine because multiple pathogenetic factors …

A series of 4-dimethylamine flavonoid derivatives 5a–5r were designed, synthesized and
evaluated as potential multi-functional anti-Alzheimer agents. The results showed that most …

A few symptomatic drugs are currently available for Alzheimer's Disease (AD) therapy, but
these molecules are only able to temporary improve the cognitive capacity of the patients if …

Alzheimer's disease (AD) is one of the most threatening diseases affecting the aged with
high incidence. Though AD has been defined for more than 100 years, it is still incurable …

Introduction: Alzheimer's disease (AD) is the most common cause of dementia. Clinical
progress in this pathogenesis field has drawn the attention of researchers, stimulating the …

Starting from nature as original source, new potential agents with pleiotropic activities have
been synthesized and evaluated as neuroprotective agents. In this work, novel nature-based …

Alzheimer's disease (AD) is a complex and progressive neurodegenerative disorder. The
available therapy is limited to the symptomatic treatment and its efficacy remains …