Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: so near and yet so far

MY Thanuja, C Anupama, SH Ranganath - Advanced drug delivery reviews, 2018 - Elsevier
Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …

Bio-inspired nanocarriers derived from stem cells and their extracellular vesicles for targeted drug delivery

M Abudurexiti, Y Zhao, X Wang, L Han, T Liu, C Wang… - Pharmaceutics, 2023 - mdpi.com
With their seemingly limitless capacity for self-improvement, stem cells have a wide range of
potential uses in the medical field. Stem-cell-secreted extracellular vesicles (EVs), as …

Design strategies and applications of circulating cell-mediated drug delivery systems

Y Su, Z Xie, GB Kim, C Dong… - ACS biomaterials science …, 2015 - ACS Publications
Drug delivery systems, particularly nanomaterial-based drug delivery systems, possess a
tremendous amount of potential to improve the diagnostic and therapeutic effects of drugs …

Engineered mesenchymal stem cells with self-assembled vesicles for systemic cell targeting

D Sarkar, PK Vemula, W Zhao, A Gupta, R Karnik… - Biomaterials, 2010 - Elsevier
Cell therapy has the potential to impact the quality of life of suffering patients. Systemic
infusion is a convenient method of cell delivery; however, the efficiency of engraftment …

Engineering cells for precision drug delivery: New advances, clinical translation, and emerging strategies

CJ Chao, E Zhang, Z Zhao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Cells have emerged as a promising new form of drug delivery carriers owing to their
distinguished advantages such as naturally bypassing immune recognition, intrinsic …

Mesenchymal stem cell-based drug delivery strategy: from cells to biomimetic

HH Wu, Y Zhou, Y Tabata, JQ Gao - Journal of Controlled Release, 2019 - Elsevier
Owing to the diversity and ease of preparation of nanomaterials, the rational nanocarriers
with a rational design have become increasingly popular in medical researches. Although …

Progress of cell‐derived biomimetic drug delivery systems for cancer therapy

T Lang, Q Yin, Y Li - Advanced Therapeutics, 2018 - Wiley Online Library
Certain types of cells possess unique characteristics such as tumor homing and prolonged
circulation in blood, which are worthy of being exploited in drug delivery carriers for cancer …

Cell-based drug delivery systems with innate homing capability as a novel nanocarrier platform

A Choi, K Javius-Jones, S Hong… - International journal of …, 2023 - Taylor & Francis
Nanoparticle-based drug delivery systems have been designed to treat various diseases.
However, many problems remain, such as inadequate tumor targeting and poor therapeutic …

Cell‐based drug delivery and use of nano‐and microcarriers for cell functionalization

AS Timin, MM Litvak, DA Gorin… - Advanced …, 2018 - Wiley Online Library
Cell functionalization with recently developed various nano‐and microcarriers for
therapeutics has significantly expanded the application of cell therapy and targeted drug …

Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise

TEG Krueger, DLJ Thorek… - Stem cells …, 2018 - academic.oup.com
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …