Summary Interleukin (IL)‐33 is a key cytokine involved in type 2 immunity and allergic
airway diseases. Abundantly expressed in lung epithelial cells, IL‐33 plays critical roles in …

Interleukin (IL)-22 is an effector cytokine, which acts primarily on epithelial cells in the skin,
gut, liver and lung. Both pro-and anti-inflammatory properties have been reported for IL-22 …

Summary Interleukin‐33 (IL‐33) is a tissue‐derived nuclear cytokine from the IL‐1 family
abundantly expressed in endothelial cells, epithelial cells and fibroblast‐like cells, both …

Abstract Interleukin‐33 (IL‐33) is a member of the IL‐1 cytokine family, which includes IL‐1
and IL‐18, and is considered to be important for host defense against nematodes by …

Summary Interleukin‐33 (IL‐33) is a member of the IL‐1 cytokine family. It predominantly
induces type 2 immune responses and thus is protective against atherosclerosis and …

Besides classic T cell‐derived T‐helper type 2 (Th2) cytokines such as IL‐4, IL‐5 and IL‐13,
tissue‐produced cytokines such as thymic stromal lymphopoietin, IL‐25 and IL‐33 are now …

IL‐33 is becoming a central molecule in allergic asthma that addresses various cascades of
innate and adaptive immune responses that lead to inflammation in the lung. Its effects are …

Rationale: IL-22 has both proinflammatory and antiinflammatory properties. Its role in
allergic lung inflammation has not been explored. Objectives: To investigate the expression …

BACKGROUND: IL-17A and IL-19 are highly expressed in chronic inflammatory diseases,
such as psoriasis and asthma. IL-19 plays a significant role in the enhancement of TH2 …

BACKGROUND: IL-22 controls tissue homeostasis by both proinflammatory and anti-
inflammatory effects. However, the anti-inflammatory mechanisms of IL-22 remain poorly …