Effects of sodium‐glucose co‐transporter 2 (SGLT2) inhibitors on serum uric acid level: a meta‐analysis of randomized controlled trials

Y Zhao, L Xu, D Tian, P Xia, H Zheng… - Diabetes, Obesity …, 2018 - Wiley Online Library
The aim of this study was to describe the effects of sodium‐glucose co‐transporter 2
(SGLT2) inhibitors on serum uric acid (SUA) in patients with type 2 diabetes mellitus (T2DM) …

[HTML][HTML] Effects of sodium glucose cotransporter-2 inhibitors on serum uric acid in type 2 diabetes mellitus: A systematic review with an indirect comparison meta …

Y Xin, Y Guo, Y Li, Y Ma, L Li, H Jiang - Saudi journal of biological sciences, 2019 - Elsevier
To describe the effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors on serum uric
acid (SUA) in patients with type 2 diabetes mellitus (T2DM). PubMed, EMBASE, and …

Effects of sodium‐glucose cotransporter 2 inhibitors on serum uric acid in patients with type 2 diabetes mellitus: a systematic review and network meta‐analysis

X Hu, Y Yang, X Hu, X Jia, H Liu… - Diabetes, Obesity and …, 2022 - Wiley Online Library
Aims The present study aims to determine the effects of sodium‐glucose cotransporter 2
(SGLT‐2) inhibitors on the serum uric acid (SUA) levels of patients with type 2 diabetes …

Effect of sodium-glucose cotransporter-2 (SGLT2) inhibitors on serum urate levels in patients with and without diabetes: a systematic review and meta-regression of 43 …

ASY Yip, S Leong, YH Teo, YN Teo… - … in Chronic Disease, 2022 - journals.sagepub.com
Objectives: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been found to reduce
serum urate in patients with type 2 diabetes mellitus. To evaluate if this effect applies to both …

SGLT2 inhibition and uric acid excretion in patients with type 2 diabetes and normal kidney function

DLS Suijk, MJB van Baar… - Clinical Journal of the …, 2022 - journals.lww.com
Results In the Renoprotective Effects of Dapagliflozin in Type 2 Diabetes study, compared
with the fasted state (5.3±1.1 mg/dl), acute hyperinsulinemia and hyperglycemia significantly …

SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria

Y Chino, Y Samukawa, S Sakai, Y Nakai… - … & drug disposition, 2014 - Wiley Online Library
ABSTRACT Sodium glucose cotransporter 2 (SGLT2) inhibitors have been reported to lower
the serum uric acid (SUA) level. To elucidate the mechanism responsible for this reduction …

Uric acid and the cardio‐renal effects of SGLT2 inhibitors

CJ Bailey - Diabetes, Obesity and Metabolism, 2019 - Wiley Online Library
Sodium/glucose co‐transporter‐2 (SGLT2) inhibitors, which lower blood glucose by
increasing renal glucose elimination, have been shown to reduce the risk of adverse …

Benefits and harms of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: a systematic review and meta-analysis

H Storgaard, LL Gluud, C Bennett, MF Grøndahl… - PloS one, 2016 - journals.plos.org
Objective Sodium-glucose co-transporter 2 inhibitors (SGLT2-i) are a novel drug class for
the treatment of diabetes. We aimed at describing the maximal benefits and risks associated …

Effects of sodium-glucose cotransporter 2 inhibitors on renal outcomes in patients with type 2 diabetes: a systematic review and meta-analysis of randomized …

JH Bae, EG Park, S Kim, SG Kim, S Hahn, NH Kim - Scientific reports, 2019 - nature.com
This study was conducted to investigate the effects of sodium-glucose cotransporter 2
(SGLT2) inhibitors on individual renal outcomes in patients with type 2 diabetes. We …

Efficacy and safety of sodium–glucose cotransporter 2 inhibitors in type 2 diabetes: a meta-analysis of randomized controlled trials for 1 to 2 years

XY Liu, N Zhang, R Chen, JG Zhao, P Yu - Journal of Diabetes and its …, 2015 - Elsevier
Aims To evaluate the mid long-term efficacy and safety of sodium–glucose cotransporter 2
(SGLT2) inhibitors in adults with type 2 diabetes mellitus (T2DM). Methods Three databases …