Bitter and sweet taste G protein-coupled receptors (known as T2Rs and T1Rs, respectively)
were originally identified in type II taste cells on the tongue, where they signal perception of …

Taste receptors are receptor proteins that detect ligands belonging to the 5 taste modalities:
sweet, bitter, sour, salty, and umami. Taste receptors are not restricted to taste cells in taste …

In addition to their recognized roles in intra-and inter-species signaling, bacterial quorum-
sensing molecules have been implicated in inter-kingdom signaling. A new study in …

The 25 bitter taste receptors (T2Rs) in humans are novel players in mediating host–
pathogen responses in the airways and innate immunity. The chemosensory T2Rs are …

Host-pathogen interactions play an important role in defining the outcome of a disease.
Recent studies have shown bacterial quorum sensing molecules (QSM) can interact with …

The upper respiratory tract is continually assaulted with harmful dusts and xenobiotics
carried on the incoming airstream. Detection of such irritants by the trigeminal nerve evokes …

Humans consciously perceive only five distinct tastes: bitter, sweet, umami [the savory taste
of monosodium glutamate (MSG)], salty, and sour. Taste cells of the tongue utilize G protein …

Taste receptors, first identified on the tongue, are best known for their role in guiding our
dietary preferences. The expression of taste receptors for umami, sweet, and bitter have …

In the upper respiratory epithelium, bitter and sweet taste receptors present in solitary
chemosensory cells influence antimicrobial innate immune defense responses. Whereas …

Taste receptors were first identified on the tongue, where they initiate a signaling pathway
that communicates information to the brain about the nutrient content or potential toxicity of …