New insights into cystic fibrosis: molecular switches that regulate CFTR
WB Guggino, BA Stanton - Nature reviews Molecular cell biology, 2006 - nature.com
Cystic fibrosis transmembrane conductance regulator (CFTR), a Cl−-selective ion channel,
is a prototypic member of the ATP-binding cassette transporter superfamily that is expressed …
is a prototypic member of the ATP-binding cassette transporter superfamily that is expressed …
[HTML][HTML] Endocytic trafficking of CFTR in health and disease
N Ameen, M Silvis, NA Bradbury - Journal of Cystic Fibrosis, 2007 - Elsevier
The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl-selective anion
channel expressed in epithelial tissues. Mutations in CFTR lead to the genetic disease cystic …
channel expressed in epithelial tissues. Mutations in CFTR lead to the genetic disease cystic …
ATP-independent CFTR channel gating and allosteric modulation by phosphorylation
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance
regulator (CFTR) channel, an ATP binding cassette (ABC) transporter. CFTR gating is linked …
regulator (CFTR) channel, an ATP binding cassette (ABC) transporter. CFTR gating is linked …
The CFTR ion channel: gating, regulation, and anion permeation
TC Hwang, KL Kirk - Cold Spring Harbor …, 2013 - perspectivesinmedicine.cshlp.org
Cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-gated anion
channel with two remarkable distinctions. First, it is the only ATP-binding cassette (ABC) …
channel with two remarkable distinctions. First, it is the only ATP-binding cassette (ABC) …
The gating of the CFTR channel
O Moran - Cellular and Molecular Life Sciences, 2017 - Springer
Cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel
expressed in the apical membrane of epithelia. Mutations in the CFTR gene are the cause of …
expressed in the apical membrane of epithelia. Mutations in the CFTR gene are the cause of …
[PDF][PDF] CFTR, a regulator of channels
K Kunzelmann, R Schreiber - The Journal of membrane biology, 1999 - academia.edu
The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated Cl−
channel that is defective in cystic fibrosis. This statement is found in most of the articles …
channel that is defective in cystic fibrosis. This statement is found in most of the articles …
CFTR function and prospects for therapy
JR Riordan - Annu. Rev. Biochem., 2008 - annualreviews.org
Mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator
(CFTR) epithelial anion channel cause cystic fibrosis (CF). The multidomain integral …
(CFTR) epithelial anion channel cause cystic fibrosis (CF). The multidomain integral …
Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partners
C Li, AP Naren - Pharmacology & therapeutics, 2005 - Elsevier
The cystic fibrosis transmembrane conductance regulator (CFTR) is the product of the gene
mutated in patients with cystic fibrosis (CF). CFTR is a cAMP-regulated chloride channel …
mutated in patients with cystic fibrosis (CF). CFTR is a cAMP-regulated chloride channel …
[HTML][HTML] CFTR Cl− channel and CFTR-associated ATP channel: distinct pores regulated by common gates
M Sugita, Y Yue, JK Foskett - The EMBO Journal, 1998 - embopress.org
The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel that
is regulated by phosphorylation of the R domain and ATP hydrolysis at two nucleotide …
is regulated by phosphorylation of the R domain and ATP hydrolysis at two nucleotide …
CFTR: a hub for kinases and crosstalk of cAMP and Ca2+
K Kunzelmann, A Mehta - The FEBS journal, 2013 - Wiley Online Library
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator
(CFTR). The resulting disease is pleiotropic consistent with the idea that CFTR acts as a …
(CFTR). The resulting disease is pleiotropic consistent with the idea that CFTR acts as a …