Computational approaches for analyzing the mechanics of atherosclerotic plaques: a review
Vulnerable and stable atherosclerotic plaques are heterogeneous living materials with
peculiar mechanical behaviors depending on geometry, composition, loading and boundary …
peculiar mechanical behaviors depending on geometry, composition, loading and boundary …
Initial stress in biomechanical models of atherosclerotic plaques
L Speelman, AC Akyildiz, B Den Adel, JJ Wentzel… - Journal of …, 2011 - Elsevier
Rupture of atherosclerotic plaques is the underlying cause for the majority of acute strokes
and myocardial infarctions. Rupture of the plaque occurs when the stress in the plaque …
and myocardial infarctions. Rupture of the plaque occurs when the stress in the plaque …
Biomechanical structural stresses of atherosclerotic plaques
Atherosclerotic plaques may rupture without warning, causing fatal clinical events such as
myocardial infarction and stroke. Degree of stenosis, which is the current criterion for …
myocardial infarction and stroke. Degree of stenosis, which is the current criterion for …
Mechanical properties of human atherosclerotic intima tissue
AC Akyildiz, L Speelman, FJH Gijsen - Journal of biomechanics, 2014 - Elsevier
Progression and rupture of atherosclerotic plaques in coronary and carotid arteries are the
key processes underlying myocardial infarctions and strokes. Biomechanical stress …
key processes underlying myocardial infarctions and strokes. Biomechanical stress …
Biomechanical factors in atherosclerosis: mechanisms and clinical implications
Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …
3D computational parametric analysis of eccentric atheroma plaque: influence of axial and circumferential residual stresses
Plaque rupture plays a role in the majority of acute coronary syndromes. Rupture has
usually been associated with stress concentrations, which are mainly affected by the plaque …
usually been associated with stress concentrations, which are mainly affected by the plaque …
On the sensitivity of wall stresses in diseased arteries to variable material properties
SD Williamson, Y Lam, HF Younis… - J. Biomech …, 2003 - asmedigitalcollection.asme.org
Accurate estimates of stress in an atherosclerotic lesion require knowledge of the material
properties of its components (eg, normal wall, fibrous plaque, calcified regions, lipid pools) …
properties of its components (eg, normal wall, fibrous plaque, calcified regions, lipid pools) …
A platform for high-fidelity patient-specific structural modelling of atherosclerotic arteries: from intravascular imaging to three-dimensional stress distributions
The pathophysiology of atherosclerotic lesions, including plaque rupture triggered by
mechanical failure of the vessel wall, depends directly on the plaque morphology-modulated …
mechanical failure of the vessel wall, depends directly on the plaque morphology-modulated …
Planar biaxial characterization of diseased human coronary and carotid arteries for computational modeling
Computational models have the potential to provide precise estimates of stresses and
strains associated with sites of coronary plaque rupture. However, lack of adequate …
strains associated with sites of coronary plaque rupture. However, lack of adequate …
A finite element investigation on plaque vulnerability in realistic healthy and atherosclerotic human coronary arteries
Atherosclerosis is the most common arterial disease. It has been shown that stresses that
are induced during blood circulation can cause plaque rupture and, in turn, lead to …
are induced during blood circulation can cause plaque rupture and, in turn, lead to …