[HTML][HTML] Distinct placental molecular processes associated with early-onset and late-onset preeclampsia
Z Ren, Y Gao, Y Gao, G Liang, Q Chen, S Jiang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Patients with preeclampsia display a spectrum of onset time and severity of
clinical presentation, yet the underlying molecular bases for the early-onset and late-onset …
clinical presentation, yet the underlying molecular bases for the early-onset and late-onset …
[HTML][HTML] Two distinct molecular faces of preeclampsia revealed by single-cell transcriptomics
I Admati, N Skarbianskis, H Hochgerner, O Ophir… - Med, 2023 - cell.com
Introduction Preeclampsia is a multisystemic, pregnancy-specific disorder united by new-
onset hypertension but with considerable variation in clinical manifestation, onset, and …
onset hypertension but with considerable variation in clinical manifestation, onset, and …
[HTML][HTML] Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology …
Preeclampsia is a syndromic disease of the mother, fetus, and placenta. The main limitation
in early and accurate diagnosis of preeclampsia is rooted in the heterogeneity of this …
in early and accurate diagnosis of preeclampsia is rooted in the heterogeneity of this …
Preeclampsia leads to dysregulation of various signaling pathways in placenta
JH Kang, H Song, JA Yoon, DY Park… - Journal of …, 2011 - journals.lww.com
Study design We performed microarray experiments to analyze genome-wide expression
profiling for 10 placentas from pregnant women with preeclampsia and 10 placentas from …
profiling for 10 placentas from pregnant women with preeclampsia and 10 placentas from …
Unsupervised placental gene expression profiling identifies clinically relevant subclasses of human preeclampsia
K Leavey, SJ Benton, D Grynspan, JC Kingdom… - …, 2016 - Am Heart Assoc
Preeclampsia (PE) is a complex, hypertensive disorder of pregnancy, demonstrating
considerable variability in maternal symptoms and fetal outcomes. Unfortunately, prior …
considerable variability in maternal symptoms and fetal outcomes. Unfortunately, prior …
The differences between early-and late-onset pre-eclampsia
AC Staff, CWG Redman - Preeclampsia: basic, genomic, and clinical, 2018 - Springer
Early-and late-onset pre-eclampsia (PE) exhibit important clinical differences both regarding
associations to foetal growth restriction as well as short-and long-term health consequences …
associations to foetal growth restriction as well as short-and long-term health consequences …
The clinical heterogeneity of preeclampsia is related to both placental gene expression and placental histopathology
Background Preeclampsia is a life-threatening disorder of pregnancy, demonstrating a high
degree of heterogeneity in clinical features such as presentation, disease severity, and …
degree of heterogeneity in clinical features such as presentation, disease severity, and …
Differential placental gene expression in preeclampsia
OBJECTIVE: Candidate genes that are associated with preeclampsia have not been
described fully. We conducted microarray and confirmatory quantitative real time …
described fully. We conducted microarray and confirmatory quantitative real time …
Gene expression profiling of placentae from women with early-and late-onset pre-eclampsia: down-regulation of the angiogenesis-related genes ACVRL1 and EGFL7 …
K Junus, M Centlow, AK Wikström… - Molecular human …, 2012 - academic.oup.com
The underlying mechanisms behind the obstetric condition pre-eclampsia (PE) are still
unclear. Manifestation of PE is heterogeneous and it has therefore been proposed to be a …
unclear. Manifestation of PE is heterogeneous and it has therefore been proposed to be a …
Systemic transcriptome comparison between early‐And late‐onset pre‐eclampsia shows distinct pathology and novel biomarkers
F Guo, B Zhang, H Yang, Y Fu, Y Wang… - Cell …, 2021 - Wiley Online Library
Objectives Pre‐eclampsia is a leading cause of morbidity and mortality during pregnancy.
Although the two forms of this disorder, early‐(EOPE) and late‐onset of pre‐eclampsia …
Although the two forms of this disorder, early‐(EOPE) and late‐onset of pre‐eclampsia …