[HTML][HTML] Microfluidic paclitaxel-loaded lipid nanoparticle formulations for chemotherapy
Nanoparticle technology has promising effects on multiple therapeutic purposes, particularly
in controlling drug delivery as Drug Delivery System. The unique properties of nanoparticles …
in controlling drug delivery as Drug Delivery System. The unique properties of nanoparticles …
A comparative study on micelles, liposomes and solid lipid nanoparticles for paclitaxel delivery
S Dattani, X Li, C Lampa, D Lechuga-Ballesteros… - International Journal of …, 2023 - Elsevier
The purpose of this work was to compare the in vitro and in vivo characteristics of LDV-
targeted lipid-based micelles, liposomes and solid lipid nanoparticles (SLN) to provide …
targeted lipid-based micelles, liposomes and solid lipid nanoparticles (SLN) to provide …
Characterization and in vitro assessment of paclitaxel loaded lipid nanoparticles formulated using modified solvent injection technique
This study investigates the design and characterization of solid lipid nanoparticles (SLNs)
containing paclitaxel fabricated by a modified solvent injection technique using stearic acid …
containing paclitaxel fabricated by a modified solvent injection technique using stearic acid …
Lipid-based nanoparticles as drug delivery system for paclitaxel in breast cancer treatment
SP de Sousa Marcial, G Carneiro, EA Leite - Journal of Nanoparticle …, 2017 - Springer
Paclitaxel (PTX) is a well-known antitumor drug, widely utilized in the treatment of breast,
ovarian, head, and neck tumors, among others. The low aqueous solubility (< 1.0 μg/mL; log …
ovarian, head, and neck tumors, among others. The low aqueous solubility (< 1.0 μg/mL; log …
Microfluidic manufacturing of phospholipid nanoparticles: Stability, encapsulation efficacy, and drug release
MGS Correia, ML Briuglia, F Niosi… - International journal of …, 2017 - Elsevier
Liposomes have been the centre of attention in research due to their potential to act as drug
delivery systems. Although its versatility and manufacturing processes are still not scalable …
delivery systems. Although its versatility and manufacturing processes are still not scalable …
Development of lipid-based nanoparticles for enhancing the oral bioavailability of paclitaxel
The current research work investigates the potential of solid lipid nanoparticles (SLNs) in
improving the oral bioavailability of paclitaxel. Paclitaxel-loaded SLNs (PTX-SLNs) were …
improving the oral bioavailability of paclitaxel. Paclitaxel-loaded SLNs (PTX-SLNs) were …
In vivo evaluation of paclitaxel-loaded lipid nanocapsules after intravenous and oral administration on resistant tumor
AC Groo, M Bossiere, L Trichard, P Legras… - …, 2015 - Future Medicine
Aim & methods: The aim of the present work was to encapsulate paclitaxel (Ptx) in various
lipid nanocapsules (LNCs) formulations and then to compare their pharmacokinetics and …
lipid nanocapsules (LNCs) formulations and then to compare their pharmacokinetics and …
An optimized two-vial formulation lipid nanoemulsion of paclitaxel for targeted delivery to tumor
L Chen, B Chen, L Deng, B Gao, Y Zhang, C Wu… - International journal of …, 2017 - Elsevier
The discovery of new intravenous drug delivery carrier for water-insoluble drug is a
challenging task. In this paper, novel two-vial formulation of paclitaxel (PTX)-loaded lipid …
challenging task. In this paper, novel two-vial formulation of paclitaxel (PTX)-loaded lipid …
[HTML][HTML] Stealth liposomes (PEGylated) containing an anticancer drug camptothecin: in vitro characterization and in vivo pharmacokinetic and tissue distribution study
D Sivadasan, MH Sultan, OA Madkhali, SH Alsabei… - Molecules, 2022 - mdpi.com
Numerous attempts to overcome the poor water solubility of cam ptothecin (CPT) by various
nano drug delivery systems are described in various sources in the literature. However, the …
nano drug delivery systems are described in various sources in the literature. However, the …
Development of new lipid-based paclitaxel nanoparticles using sequential simplex optimization
X Dong, CA Mattingly, M Tseng, M Cho… - European journal of …, 2009 - Elsevier
The objective of these studies was to develop Cremophor-free lipid-based paclitaxel (PX)
nanoparticle formulations prepared from warm microemulsion precursors. To identify and …
nanoparticle formulations prepared from warm microemulsion precursors. To identify and …