[HTML][HTML] Microfluidic paclitaxel-loaded lipid nanoparticle formulations for chemotherapy

E Jaradat, E Weaver, A Meziane… - International Journal of …, 2022 - Elsevier
Nanoparticle technology has promising effects on multiple therapeutic purposes, particularly
in controlling drug delivery as Drug Delivery System. The unique properties of nanoparticles …

A comparative study on micelles, liposomes and solid lipid nanoparticles for paclitaxel delivery

S Dattani, X Li, C Lampa, D Lechuga-Ballesteros… - International Journal of …, 2023 - Elsevier
The purpose of this work was to compare the in vitro and in vivo characteristics of LDV-
targeted lipid-based micelles, liposomes and solid lipid nanoparticles (SLN) to provide …

Characterization and in vitro assessment of paclitaxel loaded lipid nanoparticles formulated using modified solvent injection technique

D Pandita, A Ahuja, T Velpandian… - Die Pharmazie-An …, 2009 - ingentaconnect.com
This study investigates the design and characterization of solid lipid nanoparticles (SLNs)
containing paclitaxel fabricated by a modified solvent injection technique using stearic acid …

Lipid-based nanoparticles as drug delivery system for paclitaxel in breast cancer treatment

SP de Sousa Marcial, G Carneiro, EA Leite - Journal of Nanoparticle …, 2017 - Springer
Paclitaxel (PTX) is a well-known antitumor drug, widely utilized in the treatment of breast,
ovarian, head, and neck tumors, among others. The low aqueous solubility (< 1.0 μg/mL; log …

Microfluidic manufacturing of phospholipid nanoparticles: Stability, encapsulation efficacy, and drug release

MGS Correia, ML Briuglia, F Niosi… - International journal of …, 2017 - Elsevier
Liposomes have been the centre of attention in research due to their potential to act as drug
delivery systems. Although its versatility and manufacturing processes are still not scalable …

Development of lipid-based nanoparticles for enhancing the oral bioavailability of paclitaxel

D Pandita, A Ahuja, V Lather, B Benjamin, T Dutta… - Aaps Pharmscitech, 2011 - Springer
The current research work investigates the potential of solid lipid nanoparticles (SLNs) in
improving the oral bioavailability of paclitaxel. Paclitaxel-loaded SLNs (PTX-SLNs) were …

In vivo evaluation of paclitaxel-loaded lipid nanocapsules after intravenous and oral administration on resistant tumor

AC Groo, M Bossiere, L Trichard, P Legras… - …, 2015 - Future Medicine
Aim & methods: The aim of the present work was to encapsulate paclitaxel (Ptx) in various
lipid nanocapsules (LNCs) formulations and then to compare their pharmacokinetics and …

An optimized two-vial formulation lipid nanoemulsion of paclitaxel for targeted delivery to tumor

L Chen, B Chen, L Deng, B Gao, Y Zhang, C Wu… - International journal of …, 2017 - Elsevier
The discovery of new intravenous drug delivery carrier for water-insoluble drug is a
challenging task. In this paper, novel two-vial formulation of paclitaxel (PTX)-loaded lipid …

[HTML][HTML] Stealth liposomes (PEGylated) containing an anticancer drug camptothecin: in vitro characterization and in vivo pharmacokinetic and tissue distribution study

D Sivadasan, MH Sultan, OA Madkhali, SH Alsabei… - Molecules, 2022 - mdpi.com
Numerous attempts to overcome the poor water solubility of cam ptothecin (CPT) by various
nano drug delivery systems are described in various sources in the literature. However, the …

Development of new lipid-based paclitaxel nanoparticles using sequential simplex optimization

X Dong, CA Mattingly, M Tseng, M Cho… - European journal of …, 2009 - Elsevier
The objective of these studies was to develop Cremophor-free lipid-based paclitaxel (PX)
nanoparticle formulations prepared from warm microemulsion precursors. To identify and …