Outcomes after successful direct-acting antiviral therapy for patients with chronic hepatitis C and decompensated cirrhosis

MCM Cheung, AJ Walker, BE Hudson, S Verma… - Journal of …, 2016 - Elsevier
Background & Aims Direct-acting antivirals have become widely used for patients with
chronic hepatitis C virus infection with decompensated cirrhosis. Virological responses are …

Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis

GR Foster, WL Irving, MCM Cheung, AJ Walker… - Journal of …, 2016 - Elsevier
Background & Aims All oral direct acting antivirals (DAAs) effectively treat chronic hepatitis C
virus (HCV) infection, but the benefits in advanced liver disease are unclear. We compared …

A review of the treatment of chronic hepatitis C virus infection in cirrhosis

E Vezali, A Aghemo, M Colombo - Clinical therapeutics, 2010 - Elsevier
Background: Cirrhosis developing during chronic infection with the hepatitis C virus (HCV)
poses a risk of anticipated liver-related death, therefore representing a dominant indication …

Clinical outcomes in patients with chronic hepatitis C after direct-acting antiviral treatment: a prospective cohort study

F Carrat, H Fontaine, C Dorival, M Simony, C Hezode… - The Lancet, 2019 - thelancet.com
Background Although direct-acting antivirals have been used extensively to treat patients
with chronic hepatitis C virus (HCV) infection, their clinical effectiveness has not been well …

Treat chronic hepatitis C virus infection in decompensated cirrhosis–pre‐or post‐liver transplantation? The ironic conundrum in the era of effective and well‐tolerated …

C Bunchorntavakul, KR Reddy - Journal of viral hepatitis, 2016 - Wiley Online Library
The management of hepatitis C virus (HCV) infection in patients with decompensated
cirrhosis has evolved dramatically over the past few years mainly due to the availability of all …

Safety and effectiveness of direct-acting antiviral agents for treatment of patients with chronic hepatitis C virus infection and cirrhosis

R Maan, M van Tilborg, K Deterding, A Ramji… - Clinical …, 2016 - Elsevier
Background & Aims Direct-acting antivirals (DAAs) have revolutionized treatment for patients
with chronic hepatitis C virus (HCV) infection, leading to a high rates of sustained virologic …

[PDF][PDF] Treatment of hepatitis C virus infection in patients with cirrhosis and predictive value of model for end‐stage liver disease: Analysis of data from the Hepa‐C …

C Fernandez Carrillo, S Lens, E Llop, JM Pascasio… - …, 2017 - Wiley Online Library
Direct‐acting antiviral agents (DAAs) are highly effective and well tolerated in patients with
chronic hepatitis C virus infection, including those with compensated cirrhosis. However …

Survival of patients with HCV cirrhosis and sustained virologic response is similar to the general population

S Bruno, V Di Marco, M Iavarone, L Roffi… - Journal of …, 2016 - Elsevier
Background & Aims Life expectancy of patients with compensated hepatitis C virus (HCV)
cirrhosis achieving sustained virologic response (SVR) is limited by liver events as …

Reversion of disease manifestations after HCV eradication

AJ van der Meer, M Berenguer - Journal of hepatology, 2016 - Elsevier
Chronic infection with the hepatitis C virus (HCV) may lead to hepatic fibrosis and eventually
cirrhosis, at which stage, patients have a substantial risk of liver failure, hepatocellular …

Improvement of liver function parameters in advanced HCV‐associated liver cirrhosis by IFN‐free antiviral therapies

K Deterding, C Höner Zu Siederdissen… - Alimentary …, 2015 - Wiley Online Library
Background Successful antiviral treatment of decompensated hepatitis B with HBV
polymerase inhibitors is associated with improvement of liver function. To what extent liver …