[HTML][HTML] Impact of single-pill combination therapy on adherence, blood pressure control, and clinical outcomes: a rapid evidence assessment of recent literature

K Tsioufis, R Kreutz, G Sykara, J van Vugt… - Journal of …, 2020 - journals.lww.com
Objective: The 2018 European Society of Cardiology/European Society of Hypertension
Guidelines for the management of arterial hypertension raised the need for evidence to …

Adherence to single-pill versus free-equivalent combination therapy in hypertension: a systematic review and meta-analysis

G Parati, S Kjeldsen, A Coca, WC Cushman… - Hypertension, 2021 - Am Heart Assoc
Poor adherence to antihypertensive therapy is a major cause of poor blood pressure (BP)
control in patients with hypertension. Regimen simplification may improve adherence and …

The use of single-pill combinations as first-line treatment for hypertension: translating guidelines into clinical practice

E Campana, V Cunha, S Glaveckaite… - Journal of …, 2020 - journals.lww.com
Abstract The 2008 European Society of Cardiology/European Society of Hypertension
guidelines recommend the first-line prescription of two antihypertensive drugs in single-pill …

Improved persistence to medication, decreased cardiovascular events and reduced all-cause mortality in hypertensive patients with use of single-pill combinations …

RE Schmieder, S Wassmann, HG Predel, B Weisser… - …, 2023 - Am Heart Assoc
Background: Single-pill combination improves adherence and persistence to medication in
hypertension. It remains unclear whether this also reduces cardiovascular outcomes and all …

[HTML][HTML] Single pill regimen leads to better adherence and clinical outcome in daily practice in patients suffering from hypertension and/or dyslipidemia: results of a …

B Weisser, HG Predel, A Gillessen, C Hacke… - High Blood Pressure & …, 2020 - Springer
Introduction Cardiovascular diseases (CVD) represent the first cause of mortality in western
countries. Hypertension and dyslipidemia are strong risk factors for CVD, and are prevalent …

[HTML][HTML] Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: a population-based retrospective cohort study

AA Verma, W Khuu, M Tadrous, T Gomes… - PLoS …, 2018 - journals.plos.org
Background The majority of people with hypertension require more than one medication to
achieve blood pressure control. Many patients are prescribed multipill antihypertensive …

Single-pill fixed-dose drug combinations to reduce blood pressure: the right pill for the right patient

R Sarzani, G Laureti, A Gezzi… - … in Chronic Disease, 2022 - journals.sagepub.com
Arterial hypertension is one of the major causes of cardiovascular morbidity and mortality
worldwide. Effective and sustained reduction in blood pressure is essential to reduce …

Single‐pill vs free‐equivalent combination therapies for hypertension: a meta‐analysis of health care costs and adherence

B Sherrill, M Halpern, S Khan, J Zhang… - The Journal of …, 2011 - Wiley Online Library
J Clin Hypertens (Greenwich). 2011; 13: 898–909.© 2011 Wiley Periodicals, Inc. This meta‐
analysis compares health care resource use costs, adherence, and persistence between …

The impact of fixed‐dose combination versus free‐equivalent combination therapies on adherence for hypertension: a meta‐analysis

LP Du, ZW Cheng, YX Zhang, Y Li… - The Journal of Clinical …, 2018 - Wiley Online Library
Nonadherence to antihypertensive medication is considered as a reason of inadequate
control of blood pressure. This meta‐analysis aimed to systemically evaluate the impact of …

[PDF][PDF] Effectiveness of fixed-dose combination therapy in hypertension: systematic review and meta-analysis

P Kawalec, P Holko, M Gawin, A Pilc - Archives of medical science, 2018 - termedia.pl
Results Of 301 abstracts screened, 26 primary studies and 2 other meta-analyses were
identified, of which 12 studies were included in the meta-analyses and 3 studies were …