Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro

K Yu, Z Tan, Y Xin - Molecular Biology Reports, 2022 - Springer
Background Thyroid carcinoma (TC) is the most common malignant tumor of the endocrine
system. Phellinus linteus polysaccharide (PLP) physiologically acts as a suitable anti-tumor …

[HTML][HTML] Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/β-catenin in SW480 human colon …

KS Song, G Li, JS Kim, K Jing, TD Kim, JP Kim, SB Seo… - BMC cancer, 2011 - Springer
Background Polysaccharides extracted from the Phellinus linteus (PL) mushroom are known
to possess anti-tumor effects. However, the molecular mechanisms responsible for the anti …

Polysaccharides from Phellinus linteus inhibit cell growth and invasion and induce apoptosis in HepG2 human hepatocellular carcinoma cells

G Wang, L Dong, Y Zhang, Y Ji, W Xiang, M Zhao - Biologia, 2012 - Springer
It has been demonstrated that the medicinal mushroom Phellinus linteus (PL), which
consists mainly of polysaccharides, possesses antitumor and immunomodulatory properties …

LHPP inhibits cell growth and migration and triggers autophagy in papillary thyroid cancer by regulating the AKT/AMPK/mTOR signaling pathway

W Sun, K Qian, K Guo, L Chen, J Xiang… - Acta biochimica et …, 2020 - academic.oup.com
In recent decades, the incidence rate of papillary thyroid carcinoma (PTC) has been rapidly
increasing. However, the molecular mechanism of the physiological and pathological …

A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells by targeting of Cdc42 and 67 kDa Laminin …

Y Li, D Li, J Chen, S Wang - International journal of biological …, 2016 - Elsevier
In this study, we isolated and purified a polysaccharide (PTPA) from the tubers of Pinellia
ternate. We aimed to evaluate the cytotoxic effects of PTPA on human cholangiocarcinoma …

Polysaccharide from Phellinus linteus induces S-phase arrest in HepG2 cells by decreasing calreticulin expression and activating the P27kip1–cyclin A/D1/E–CDK2 …

YG Li, DF Ji, S Zhong, PG Liu, ZQ Lv, JX Zhu… - Journal of …, 2013 - Elsevier
Ethnopharmacology relevance Our previous study showed that the proteoglycan P1 from
Phellinus linteus (Mesima) exhibits significant anti-tumor activity against human …

Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells

G Li, DH Kim, TD Kim, BJ Park, HD Park, JI Park… - Cancer letters, 2004 - Elsevier
The cytotoxic mechanism of protein-bound polysaccharide isolated from Phellinus linteus
(PL, Mesima®) has been investigated. PL inhibited the proliferation and colony formation of …

Lepista sordida polysaccharide induces apoptosis of Hep-2 cancer cells via mitochondrial pathway

S Miao, X Mao, R Pei, S Miao, C Xiang, Y Lv… - International journal of …, 2013 - Elsevier
In our previous study, a potential antitumor polysaccharide (LSPc1) was screened from the
fruiting bodies of Lepista sordida. However, its molecular mechanism of cell death induction …

Laminaria japonica polysaccharides effectively inhibited the growth of nasopharyngeal carcinoma cells in vivo and in vitro study

M Zeng, X Wu, F Li, W She, L Zhou, B Pi, Z Xu… - Experimental and …, 2017 - Elsevier
Abstract Aims Laminaria Japonica Polysaccharides (LJP) is a kind of plant polysaccharide
isolated from Laminaria Japonica Aresch. LJP has a variety of biological activity, including …

Antitumor and immunomodulation activities of polysaccharide from Phellinus baumii

MM Liu, P Zeng, XT Li, LG Shi - International Journal of Biological …, 2016 - Elsevier
A homogeneous polysaccharide (PPB) was purified from fruiting bodies of Phellinus baumii.
And in vitro antitumor and immunomodulation activities were investigated on HeLa, SGC …