The potential value of the PI3K/Akt/mTOR signaling pathway for assessing prognosis in cervical cancer and as a target for therapy
A Bahrami, M Hasanzadeh… - Journal of cellular …, 2017 - Wiley Online Library
Cervical cancer is a common gynecological cancer and a leading cause of cancer‐related
death in women globally. There is a need for the identification of prognostic and predictive …
death in women globally. There is a need for the identification of prognostic and predictive …
Phosphatidylinositol 3-kinase signaling as a therapeutic target for cervical cancer
J Wu, C Chen, KN Zhao - Current cancer drug targets, 2013 - ingentaconnect.com
Cervical cancer is the second most frequent cause of female cancer mortality and remains a
major health problem in women worldwide. Surgery, chemotherapy and radiotherapy alone …
major health problem in women worldwide. Surgery, chemotherapy and radiotherapy alone …
Elevated phosphatidylinositol 3-kinase activation and its clinicopathological significance in cervical cancer
XY Zhang, HY Zhang, PN Zhang, X Lu, H Sun - European Journal of …, 2008 - Elsevier
OBJECTIVE: The objective was to study the role of PI3K signaling in the development of
cervical cancer and the antitumor effect of PI3K inhibitors. STUDY DESIGN: PI3K protein and …
cervical cancer and the antitumor effect of PI3K inhibitors. STUDY DESIGN: PI3K protein and …
The importance of the PI3K/AKT/MTOR pathway in the progression of ovarian cancer
ZC Dobbin, CN Landen - International journal of molecular sciences, 2013 - mdpi.com
Ovarian cancer is the fifth most common cause of death due to cancer in women despite
being the tenth in incidence. Unfortunately, the five-year survival rate is only 45%, which has …
being the tenth in incidence. Unfortunately, the five-year survival rate is only 45%, which has …
Role of pi3k/akt/mtor in cancer signaling
N Owusu-Brackett, M Shariati… - Predictive biomarkers in …, 2019 - Springer
Abstract Phosphatidylinositol 3-kinases (PI3K)/AKT/mammalian target of rapamycin (mTOR)
pathway plays a crucial role in integrating a variety of extracellular stimuli to regulate growth …
pathway plays a crucial role in integrating a variety of extracellular stimuli to regulate growth …
Pathway-specific analysis of gene expression data identifies the PI3K/Akt pathway as a novel therapeutic target in cervical cancer
JK Schwarz, JE Payton, R Rashmi, T Xiang, Y Jia… - Clinical Cancer …, 2012 - AACR
Purpose: Cervical tumor response on posttherapy 2 [18F] fluoro-2-deoxy-d-glucose-positron
emission tomography (FDG-PET) is predictive of survival outcome. The purpose of this study …
emission tomography (FDG-PET) is predictive of survival outcome. The purpose of this study …
Role of PI3K/AKT pathway in squamous cell carcinoma with an especial focus on head and neck cancers
S Ghafouri-Fard, A Noie Alamdari… - Cancer Cell …, 2022 - Springer
Abstract PI3K/AKT pathway is an important pathway in the carcinogenesis since it has
central impacts in the regulation of metabolic pathways, cell proliferation and survival, gene …
central impacts in the regulation of metabolic pathways, cell proliferation and survival, gene …
The role of signaling pathways in cervical cancer and molecular therapeutic targets
J Manzo-Merino, A Contreras-Paredes… - Archives of medical …, 2014 - Elsevier
Cervical cancer is a public health issue in developing countries. Although the Pap smear
and colposcopy remain the major strategies for detection, most cases are diagnosed in the …
and colposcopy remain the major strategies for detection, most cases are diagnosed in the …
Research progress on the PI3K/AKT signaling pathway in gynecological cancer
X Shi, J Wang, Y Lei, C Cong… - Molecular medicine …, 2019 - spandidos-publications.com
Abstract The phosphatidylinositol 3‑kinase (PI3K)/protein kinase B (AKT) signaling pathway
is involved in the regulation of multiple cellular physiological processes by activating …
is involved in the regulation of multiple cellular physiological processes by activating …
PI3K/AKT/mTOR signaling pathway as a therapeutic target for ovarian cancer
HX Li, JF Zeng, K Shen - Archives of gynecology and obstetrics, 2014 - Springer
Background Ovarian cancer is one of the major causes of death in women worldwide.
Despite improvements in conventional treatment approaches, such as surgery and …
Despite improvements in conventional treatment approaches, such as surgery and …