Life-course socioeconomic status and DNA methylation of genes regulating inflammation

S Stringhini, S Polidoro, C Sacerdote… - International journal …, 2015 - academic.oup.com
Background: In humans, low socioeconomic status (SES) across the life course is
associated with greater diurnal cortisol production, increased inflammatory activity and …

Circulating levels of inflammatory markers and DNA methylation, an analysis of repeated samples from a population based cohort

R Myte, A Sundkvist, B Van Guelpen, S Harlid - Epigenetics, 2019 - Taylor & Francis
ABSTRACT DNA methylation in blood may adapt to conditions affecting our health, such as
inflammation, and multiple studies have identified differential DNA methylation related to …

Life course socioeconomic status and DNA methylation in genes related to stress reactivity and inflammation: the multi-ethnic study of atherosclerosis

BL Needham, JA Smith, W Zhao, X Wang… - Epigenetics, 2015 - Taylor & Francis
Epigenetic changes, such as DNA methylation, have been hypothesized to provide a link
between the social environment and disease development. The purpose of this study was to …

Epigenetics and inflammatory markers: a systematic review of the current evidence

V Gonzalez-Jaramillo… - International journal …, 2019 - Wiley Online Library
Epigenetic mechanisms have been suggested to play a role in the genetic regulation of
pathways related to inflammation. Therefore, we aimed to systematically review studies …

Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation

G Fiorito, S Polidoro, PA Dugué, M Kivimaki, E Ponzi… - Scientific reports, 2017 - nature.com
Low socioeconomic status (SES) is associated with earlier onset of age-related chronic
conditions and reduced life-expectancy, but the underlying biomolecular mechanisms …

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

S Ligthart, C Marzi, S Aslibekyan, MM Mendelson… - Genome biology, 2016 - Springer
Background Chronic low-grade inflammation reflects a subclinical immune response
implicated in the pathogenesis of complex diseases. Identifying genetic loci where DNA …

Genome‐wide analysis of DNA methylation in relation to socioeconomic status during development and early adulthood

TW McDade, CP Ryan, MJ Jones… - American journal of …, 2019 - Wiley Online Library
Objectives Socioeconomic status (SES) is a powerful determinant of health, but the
underlying biological mechanisms are poorly understood. This study investigates whether …

Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: The Multi-Ethnic Study of Atherosclerosis

JA Smith, W Zhao, X Wang, SM Ratliff, B Mukherjee… - Epigenetics, 2017 - Taylor & Francis
Living in a disadvantaged neighborhood is associated with poor health outcomes even after
accounting for individual-level socioeconomic factors. The chronic stress of unfavorable …

Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood

TW McDade, C Ryan, MJ Jones… - Proceedings of the …, 2017 - National Acad Sciences
Chronic inflammation contributes to a wide range of human diseases, and environments in
infancy and childhood are important determinants of inflammatory phenotypes. The …

Associations with early-life socio-economic position in adult DNA methylation

N Borghol, M Suderman, W McArdle… - International journal …, 2012 - academic.oup.com
Background Disadvantaged socio-economic position (SEP) in childhood is associated with
increased adult mortality and morbidity. We aimed to establish whether childhood SEP was …