MCP-1: Function, regulation, and involvement in disease

S Singh, D Anshita, V Ravichandiran - International immunopharmacology, 2021 - Elsevier
Abstract MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif)
ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of …

Monocyte chemoattractant protein-1: a key mediator in inflammatory processes

E Melgarejo, MÁ Medina, F Sánchez-Jiménez… - The international journal …, 2009 - Elsevier
Monocyte chemoattractant protein-1 (MCP-1) is a potent chemoattractant for monocytes and
macrophages to areas of inflammation. MCP-1 is a prototypical chemokine subject to …

MCP-1: chemoattractant with a role beyond immunity: a review

A Yadav, V Saini, S Arora - Clinica chimica acta, 2010 - Elsevier
BACKGROUND: Monocyte Chemoattractant Protein (MCP)-1, a potent monocyte attractant,
is a member of the CC chemokine subfamily. MCP-1 exerts its effects through binding to G …

Impact of MCP-1 in atherosclerosis

J Lin, V Kakkar, X Lu - Current pharmaceutical design, 2014 - ingentaconnect.com
Monocyte chemotactic protein-1 (MCP-1)(also referred to as chemokine (CC motif) ligand 2
(CCL2) is expressed by mainly inflammatory cells and endothelial cells. The expression …

[HTML][HTML] MCP‑1 targeting: Shutting off an engine for tumor development

L Wang, J Lan, J Tang, N Luo - Oncology letters, 2022 - spandidos-publications.com
A large amount of research has proven that monocyte chemotactic protein‑1 (MCP‑1) is
associated with different types of disease, including autoimmune, metabolic and …

[HTML][HTML] Systemic MCP-1 levels derive mainly from injured liver and are associated with complications in cirrhosis

A Queck, H Bode, FE Uschner, MJ Brol, C Graf… - Frontiers in …, 2020 - frontiersin.org
Background and Aims: Monocyte chemotactic protein-1 (MCP-1) is a potent chemoattractant
for monocytes. It is involved in pathogenesis of several inflammatory diseases. Hepatic MCP …

Role of MCP-1 in cardiovascular disease: molecular mechanisms and clinical implications

J Niu, PE Kolattukudy - Clinical science, 2009 - portlandpress.com
Many of the major diseases, including cardiovascular disease, are widely recognized as
inflammatory diseases. MCP-1 (monocyte chemotactic protein-1) plays a critical role in the …

Monocyte chemoattractant protein-1 (MCP-1): an overview

SL Deshmane, S Kremlev, S Amini… - Journal of interferon & …, 2009 - liebertpub.com
Chemokines constitute a family of chemoattractant cytokines and are subdivided into four
families on the basis of the number and spacing of the conserved cysteine residues in the N …

Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes

J Panee - Cytokine, 2012 - Elsevier
Monocyte Chemoattractant Protein-1 (MCP-1) is the first discovered and most extensively
studied CC chemokine, and the amount of studies on its role in the etiologies of obesity-and …

[HTML][HTML] Roles of MCP-1 in development of HIV-dementia

NK Dhillon, R Williams, S Callen, C Zien… - … in bioscience: a …, 2008 - ncbi.nlm.nih.gov
The encephalopathy caused by HIV, known clinically as HIV-associated dementia (HAD)
and pathologically as HIV encephalitis (HIVE), results from intense infiltration of …