GLT-1, the major glutamate transporter in the mammalian central nervous system, is
expressed in presynaptic terminals that use glutamate as a neurotransmitter, in addition to …

The glutamate transporter GLT-1 is highly expressed in astrocytes but also in neurons,
primarily in axon terminals. We generated a conditional neuronal GLT-1 KO using synapsin …

Historically, glutamate uptake in the CNS was mainly attributed to glial cells for three
reasons: 1) none of the glutamate transporters were found to be located in presynaptic …

The astrocytic GLT‐1 (or EAAT2) is the major glutamate transporter for clearing synaptic
glutamate. While the diffusion dynamics of neurotransmitter receptors at the neuronal …

GLT-1 (EAAT2; slc1a2) is the major glutamate transporter in the brain, and is predominantly
expressed in astrocytes, but at lower levels also in excitatory terminals. We generated a …

Expression of the glutamate transporter GLT-1 in neurons has been shown to be important
for synaptic mitochondrial function in the cerebral cortex. Here we determined whether …

To identify glutamate transporters expressed in forebrain neurons, we prepared a cDNA
library from rat forebrain neuronal cultures, previously shown to transport glutamate with …

Rationale GLT-1 is the major glutamate transporter in the brain and is expressed
predominantly in astrocytes but is also present in excitatory axon terminals. To understand …

Cortical spreading depression (CSD) is a pathological neural excitation that underlies
migraine pathophysiology. Since glutamate receptor antagonists impair CSD propagation …

Astrocytes express the sodium‐dependent glutamate transporters GLAST and GLT‐1, which
are critical to maintain low extracellular glutamate concentrations. Here, we analyzed …