Aims To explore the involvement of NOD‐like receptor protein 3 (NLRP3) inflammasome
and M1 macrophage in root resorption (RR). Methods A rat RR model was established by …

Background The NLRP3 inflammasome plays an important role in the cellular defense
against invading pathogens and is reported to be expressed in human dental pulp …

This study investigates the role of NLRP3 inflammasome and its main effector Caspase-1 in
inflammation and alveolar bone resorption associated with periodontitis. Heat-killed …

The cause of chronic inflammatory periodontitis, which leads to the destruction of
periodontal ligament and alveolar bone, is multifactorial. An increasing number of studies …

Inflammasomes serve as an intracellular machinery to initiate inflammatory response to
various danger signals. However, the chronic periodontitis pathological relevance of this …

Objective Porphyromonas gingivalis is involved in the pathogenesis of chronic inflammatory
periodontal disease. Recent studies have suggested that the NLRP3 inflammasome plays …

Objectives NLRP3 inflammasome is a critical part of the innate immune system and plays an
important role in a variety of inflammatory diseases. However, the effects of NLRP3 …

Recognition of pathogen-associated molecular patterns that activate IL-1β is regulated by
inflammasomes, predominantly of the nucleotide-binding oligomerization domain-like …

Background Nod‐like receptor family pyrin domain‐containing protein‐3 (NLRP3) complex
inflammasome has potentially been shown to play an important role in the development of …

Mechanical force–induced orthodontic root resorption is a major clinical challenge in
orthodontic treatment. Macrophages play an important role in orthodontic root resorption, but …