Natural killer cell function is well preserved in asymptomatic human immunodeficiency virus type 2 (HIV-2) infection but similar to that of HIV-1 infection when CD4 T …

SV Nuvor, M van der Sande, S Rowland-Jones… - Journal of …, 2006 - Am Soc Microbiol
Natural killer (NK) cells are potent effectors of natural immunity and their activity prevents
human immunodeficiency virus type 1 (HIV-1) viral entry and viral replication. We sought to …

[HTML][HTML] Changes in Natural Killer cell activation and function during primary HIV-1 Infection

V Naranbhai, M Altfeld, SSA Karim, T Ndung'u… - PloS one, 2013 - journals.plos.org
Background Recent reports suggest that Natural Killer (NK) cells may modulate
pathogenesis of primary HIV-1 infection. However, HIV dysregulates NK-cell responses. We …

Frequent and strong antibody-mediated natural killer cell activation in response to HIV-1 Env in individuals with chronic HIV-1 infection

CF Thobakgale, L Fadda, K Lane, I Toth… - Journal of …, 2012 - Am Soc Microbiol
Natural killer (NK) cells play a critical role in the control of HIV-1 infection, and NK cells that
respond to HIV-1 peptides have been recently described. However, the mechanisms by …

Increased natural killer cell activity in viremic HIV-1 infection

G Alter, JM Malenfant, RM Delabre… - The Journal of …, 2004 - journals.aai.org
NK cells are a subset of granular lymphocytes that are critical in the innate immune
response to infection. These cells are capable of killing infected cells and secreting integral …

Natural killer cell inhibits human immunodeficiency virus replication in chronically infected immune cells

T Zhang, Y Li, YJ Wang, X Wang, M Young… - Antiviral research, 2007 - Elsevier
Natural killer (NK) cells are a crucial component of the host innate immune system. We
investigated the noncytolytic anti-human immunodeficiency virus (HIV) activity of NK cells in …

[HTML][HTML] Increased natural killer cell activation in HIV-infected immunologic non-responders correlates with CD4+ T cell recovery after antiretroviral therapy and viral …

Z Luo, Z Li, L Martin, Z Hu, H Wu, Z Wan, M Kilby… - PLoS …, 2017 - journals.plos.org
The role of natural killer (NK) cell function in HIV disease especially in the setting of long-
term antiretroviral therapy (ART) and viral suppression is not fully understood. In the current …

Normalization of natural killer cell function and phenotype with effective anti-HIV therapy and the role of IL-10

KG Parato, A Kumar, AD Badley, JL Sanchez-Dardon… - Aids, 2002 - journals.lww.com
Objectives Natural killer (NK) cell function is likely to be important in controlling HIV infection
and opportunistic pathogens. We therefore evaluated NK function and phenotype over the …

A comparative study of the impact of HIV infection on natural killer cell number and function in Thais and North Americans

MS De Souza, C Karnasuta, AE Brown… - AIDS research and …, 2000 - liebertpub.com
Innate immunity may play a role in preventing HIV infection and progression to AIDS. Most
studies of natural killer (NK) cell function have been conducted in populations with different …

Natural killer cell function in patients with acquired immunodeficiency syndrome and related diseases

BG Brenner, A Dascal, RG Margolese… - Journal of Leukocyte …, 1989 - Wiley Online Library
This review describes current knowledge of changes in natural killer (NK) cell function in
acquired immunodeficiency syndrome (AIDS)‐related disorders, vis‐à‐vis associated …

Natural killer cells in HIV-1 infection: role of NK cell-mediated non-cytolytic mechanisms in pathogenesis of HIV-1 infection

S Kottilil - 2003 - nopr.niscpr.res.in
Natural killer (NK) cells exhibit both cytolytic and non-cytolytic effector functions against HIV-
infected targets. Their precise rule in immunopathogenesis of HIV-1 infection is, yet to be …