Adjuvants are vaccine components that enhance the magnitude, breadth and durability of
the immune response. Following its introduction in the 1920s, alum remained the only …

Vaccinations are one of the most important preventive tools against infectious diseases.
Over time, many different types of vaccines have been developed concerning the antigen …

In the last decade there have been some significant advances in vaccine adjuvants,
particularly in relation to their inclusion in licensed products. This was proceeded by several …

Vaccines were first introduced more than 200 years ago and have since played a key role in
the reduction of morbidity and mortality caused by infectious diseases. Many of the safest …

Adjuvant design has historically had a touch of alchemy at its heart due to its reliance on the
complex biology of innate immune activation. However, a new mechanistic understanding of …

Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Vaccines containing novel adjuvant formulations are increasingly reaching advanced
development and licensing stages, providing new tools to fill previously unmet clinical …

Highlights•Adjuvants can be incorporated into vaccines to enhance the magnitude,
functionality, breadth and durability of antigen-specific immune responses.•A deeper …

The discovery and wide spread use of vaccines have saved millions of lives in the past few
decades. Vaccine adjuvants represent an integral part of the modern vaccines. Despite …

The current COVID-19 pandemic, caused by severe acute respiratory syndrome-coronavirus
2 (SARS-CoV-2), has raised significant economic, social, and psychological concerns. The …