Antiprotozoal drugs: challenges and opportunities

CT Supuran - Expert Opinion on Therapeutic Patents, 2023 - Taylor & Francis
Protozoans are widespread organisms in most habitats worldwide, being a paraphyletic
group with an intricate evolutionary history [1, 2]. There is a multitude of phyla, genera, and …

Antiprotozoal agents: How have they changed over a decade?

VS Fernandes, R da Rosa, LA Zimmermann… - Archiv der …, 2022 - Wiley Online Library
Neglected tropical diseases are a diverse group of communicable diseases that are
endemic in low‐or low‐to‐middle‐income countries located in tropical and subtropical …

Challenges and promises for obtaining new antiprotozoal drugs: what's going wrong?

AB Vermelho, M Mori, WA Donald… - … drug development and …, 2022 - Springer
Infections by protozoa can cause some of the most serious human diseases, particularly in
tropical regions. However, the number of available drugs used to treat such diseases tends …

Antiprotozoal compounds: state of the art and new developments

F Astelbauer, J Walochnik - International Journal of Antimicrobial Agents, 2011 - Elsevier
Protozoa can cause severe diseases, including malaria, leishmaniasis, Chagas disease,
sleeping sickness and amoebiasis, all being responsible for morbidity and mortality …

Human antiprotozoal therapy: past, present, and future

M Khaw, CB Panosian - Clinical Microbiology Reviews, 1995 - Am Soc Microbiol
Human protozoal infections are ubiquitous and occur worldwide. In many cases,
antiprotozoal agents currently in use predate the modern antibiotic era. Despite the relative …

[图书][B] Antiprotozoal drug development and delivery

AB Vermelho, CT Supuran - 2022 - Springer
Protozoans are microscopic, nonfilamentous protists belonging to a multitude of phyla, with
several genera and species described so far, many of which possess ecological and …

Antiparasitic drugs

LX Liu, PF Weller - New England Journal of Medicine, 1996 - Mass Medical Soc
Infections with parasitic helminths and protozoa are important causes of morbidity and
mortality worldwide. Chemotherapy has an important role not only in the treatment of …

Old antiprotozoal drugs: are they still viable options for parasitic infections or new options for other diseases?

S Cortez-Maya, A Moreno-Herrera… - Current Medicinal …, 2020 - ingentaconnect.com
Parasitic diseases, caused by helminths (ascariasis, hookworm, trichinosis, and
schistosomiasis) and protozoa (chagas, leishmaniasis, and amebiasis), are considered a …

The management of Babesia, amoeba and other zoonotic diseases provoked by protozoa

C Capasso, CT Supuran - Expert Opinion on Therapeutic Patents, 2023 - Taylor & Francis
Introduction There are 12 protozoan genera that provoke zoonotic disease in humans and
animals. We discuss the most common ones with a highlight on Babesia spp and …

[HTML][HTML] Drug development to protozoan diseases

L Monzote, A Siddiq - The Open Medicinal Chemistry Journal, 2011 - ncbi.nlm.nih.gov
The diseases caused by protozoan parasite are responsible for considerable mortality and
morbidity, affecting more than 500 million of people in the world. The epidemiological control …