Plasticity at glycinergic synapses in dorsal cochlear nucleus of rats with behavioral evidence of tinnitus
Fifteen percent to 35% of the United States population experiences tinnitus, a subjective
“ringing in the ears”. Up to 10% of those afflicted report severe and disabling symptoms …
“ringing in the ears”. Up to 10% of those afflicted report severe and disabling symptoms …
Inhibitory neurotransmission in animal models of tinnitus: maladaptive plasticity
Tinnitus is a phantom auditory sensation experienced by up to 14% of the United States
population with a smaller percentage experiencing decreased quality of life. A compelling …
population with a smaller percentage experiencing decreased quality of life. A compelling …
Noise overexposure alters long-term somatosensory-auditory processing in the dorsal cochlear nucleus—possible basis for tinnitus-related hyperactivity?
S Dehmel, S Pradhan, S Koehler… - Journal of …, 2012 - Soc Neuroscience
The dorsal cochlear nucleus (DCN) is the first neural site of bimodal auditory-somatosensory
integration. Previous studies have shown that stimulation of somatosensory pathways …
integration. Previous studies have shown that stimulation of somatosensory pathways …
[HTML][HTML] The reduced cochlear output and the failure to adapt the central auditory response causes tinnitus in noise exposed rats
L Rüttiger, W Singer, R Panford-Walsh, M Matsumoto… - PloS one, 2013 - journals.plos.org
Tinnitus is proposed to be caused by decreased central input from the cochlea, followed by
increased spontaneous and evoked subcortical activity that is interpreted as compensation …
increased spontaneous and evoked subcortical activity that is interpreted as compensation …
[HTML][HTML] Bilateral dorsal cochlear nucleus lesions prevent acoustic-trauma induced tinnitus in an animal model
TJ Brozoski, KW Wisner, LT Sybert… - Journal of the Association …, 2012 - Springer
Animal experiments suggest that chronic tinnitus (“ringing in the ears”) may result from
processes that overcompensate for lost afferent input. Abnormally elevated spontaneous …
processes that overcompensate for lost afferent input. Abnormally elevated spontaneous …
Elevated fusiform cell activity in the dorsal cochlear nucleus of chinchillas with psychophysical evidence of tinnitus
TJ Brozoski, CA Bauer, DM Caspary - Journal of Neuroscience, 2002 - Soc Neuroscience
Chinchillas with psychophysical evidence of chronic tinnitus were shown to have
significantly elevated spontaneous activity and stimulus-evoked responses in putative …
significantly elevated spontaneous activity and stimulus-evoked responses in putative …
Remodeling of cholinergic input to the hippocampus after noise exposure and tinnitus induction in Guinea pigs
Here, we investigate remodeling of hippocampal cholinergic inputs after noise exposure and
determine the relevance of these changes to tinnitus. To assess the effects of noise …
determine the relevance of these changes to tinnitus. To assess the effects of noise …
[HTML][HTML] Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus
AS Lowe, JP Walton - PLoS One, 2015 - journals.plos.org
Chronic tinnitus, or “ringing of the ears”, affects upwards of 15% of the adult population.
Identifying a cost-effective and objective measure of tinnitus is needed due to legal concerns …
Identifying a cost-effective and objective measure of tinnitus is needed due to legal concerns …
Mechanisms of synaptic plasticity in the dorsal cochlear nucleus: plasticity-induced changes that could underlie tinnitus
T Tzounopoulos - 2008 - ASHA
Purpose Tinnitus is the persistent perception of a subjective sound. Tinnitus is almost
universally experienced in some forms. In most cases, recovery may occur in seconds …
universally experienced in some forms. In most cases, recovery may occur in seconds …
Diminished cortical inhibition in an aging mouse model of chronic tinnitus
Flavoprotein autofluorescence imaging was used to examine auditory cortical synaptic
responses in aged animals with behavioral evidence of tinnitus and hearing loss. Mice were …
responses in aged animals with behavioral evidence of tinnitus and hearing loss. Mice were …