[HTML][HTML] Electroacupuncture alleviates mechanical allodynia in a rat model of complex regional pain syndrome type-I via suppressing spinal CXCL12/CXCR4 …

Q Hu, X Zheng, X Li, B Liu, C Yin, Y Li, R Chen… - The Journal of …, 2020 - Elsevier
Complex regional pain syndrome (CRPS) results in chronic and excruciating pain in
patients. Conventional therapies lack effectiveness, rendering it one of the most difficult to …

[HTML][HTML] Electroacupuncture alleviates mechanical allodynia of a rat model of CRPS-I and modulates gene expression profiles in dorsal root ganglia

J Wang, X Zheng, B Liu, C Yin, R Chen, X Li… - Frontiers in …, 2020 - frontiersin.org
Complex regional pain syndrome type-I (CRPS-I) is chronic neurological disorder
accompanied with devastating pain. Most conventional medical treatments lack …

Inhibition of chemokine CX3CL1 in spinal cord mediates the electroacupuncture-induced suppression of inflammatory pain

Y Li, Z Fang, N Gu, F Bai, Y Ma, H Dong… - Journal of pain …, 2019 - Taylor & Francis
Purpose Chemokine CX3CL1 and its receptor CX3CR1 in the lumbar spinal cord play
crucial roles in pain processing. Electroacupuncture (EA) is recognized as an alternative …

Nrf2 Activation Mediates Antiallodynic Effect of Electroacupuncture on a Rat Model of Complex Regional Pain Syndrome Type‐I through Reducing Local Oxidative …

X Li, C Yin, Q Hu, J Wang, H Nie, B Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Complex regional pain syndrome type‐I (CRPS‐I) represents a type of neurovascular
condition featured by severe pain in affected extremities. Few treatments have proven …

Electroacupuncture attenuates cancer-induced bone pain via NF-κB/CXCL12 signaling in midbrain periaqueductal gray

M Xu, Y Fei, Q He, J Fu, J Zhu, J Tao, C Ni… - ACS Chemical …, 2021 - ACS Publications
Electroacupuncture (EA) is effective in various chronic pains. NF-κB and CXCL12 modulate
the formation of chronic pain. Herein, we hypothesized that EA alleviates cancer-induced …

Electroacupuncture induces antihyperalgesic effect through endothelin-B receptor in the chronic phase of a mouse model of complex regional pain syndrome type I

L Mazzardo-Martins, DC Salm… - … -European Journal of …, 2018 - Springer
Complex regional pain syndrome (CRPS) is a disorder that involves abnormal inflammation
and nerve dysfunction frequently resistant to a broad range of treatments. Peripheral nerve …

[HTML][HTML] Electroacupuncture mediates extracellular signal-regulated kinase 1/2 pathways in the spinal cord of rats with inflammatory pain

JQ Fang, JF Fang, Y Liang, JY Du - BMC Complementary and Alternative …, 2014 - Springer
Background Activation of extracellular signal-regulated kinase1/2 (ERK1/2) in dorsal horn of
the spinal cord by peripheral inflammation is contributed to inflammatory pain …

Expression profiling of L5-S2 spinal cord dorsal horn in a rat model of chronic pelvic pain syndrome uncovers potential mechanism of electroacupuncture mediated …

C Xu, K Cheng, XL Wu, HY Tai, YM Chai… - Journal of Pain …, 2022 - Taylor & Francis
Purpose We aim to explore expression profiles of genes in SCDH of CPPS model rat
relevant to pain and inflammation by RNA-Seq and to investigate the mechanism of anti …

Electroacupuncture attenuates mechanical allodynia by suppressing the spinal JNK1/2 pathway in a rat model of inflammatory pain

JY Du, JQ Fang, Y Liang, JF Fang - Brain Research Bulletin, 2014 - Elsevier
Background Electroacupuncture (EA) has a substantial analgesic effect on inflammatory
pain induced by complete Freund's adjuvant (CFA). The activation of the c-Jun N-terminal …

Electroacupuncture ameliorates pain in cervical spondylotic radiculopathy rat by inhibiting the CaMKII/CREB/BDNF signaling pathway and regulating spinal synaptic …

H Su, H Chen, X Zhang, S Su, J Li, Y Guo… - Brain and …, 2023 - Wiley Online Library
Background Central sensitization is one of the important mechanisms underlying
neuropathic and radicular pain due to cervical spondylotic radiculopathy (CSR). Recent …