Immune checkpoint inhibitor therapy in patients with preexisting inflammatory bowel disease
PURPOSE The risk of immune checkpoint inhibitor therapy–related GI adverse events in
patients with cancer and inflammatory bowel disease (IBD) has not been well described. We …
patients with cancer and inflammatory bowel disease (IBD) has not been well described. We …
Systematic review with meta‐analysis: safety and tolerability of immune checkpoint inhibitors in patients with pre‐existing inflammatory bowel diseases
J Meserve, A Facciorusso, AK Holmer… - Alimentary …, 2021 - Wiley Online Library
Background Immune checkpoint inhibitors may variably impact patients with pre‐existing
autoimmune diseases. Aims To evaluate the risks and outcomes of adverse events in …
autoimmune diseases. Aims To evaluate the risks and outcomes of adverse events in …
Risk of gastrointestinal complications in cancer patients treated with immune checkpoint inhibitors: a meta-analysis
O Abdel-Rahman, H ElHalawani, M Fouad - Immunotherapy, 2015 - Taylor & Francis
Aim: We performed a meta-analysis of the risk of selected gastrointestinal toxicities
associated with immune checkpoint inhibitors. Patients & methods: Eligible studies included …
associated with immune checkpoint inhibitors. Patients & methods: Eligible studies included …
[HTML][HTML] Concurrent therapy with immune checkpoint inhibitors and TNFα blockade in patients with gastrointestinal immune-related adverse events
Background Immune checkpoint inhibitors (ICI) have demonstrated remarkable efficacy as
cancer therapeutics, however, their use remains limited due to the development of immune …
cancer therapeutics, however, their use remains limited due to the development of immune …
[HTML][HTML] Immune checkpoint Inhibitor–Induced diarrhea and Colitis: Incidence and Management. A systematic review and Meta-analysis
DL Nielsen, CB Juhl, IM Chen, L Kellermann… - Cancer Treatment …, 2022 - Elsevier
Abstract Background Immune checkpoint inhibitors (ICIs) have improved cancer outcomes.
However, immune-related adverse effects are common. The aim was to investigate the …
However, immune-related adverse effects are common. The aim was to investigate the …
[HTML][HTML] Importance of endoscopic and histological evaluation in the management of immune checkpoint inhibitor-induced colitis
Background Immune checkpoint inhibitors (ICPI) are efficacious treatments for advanced
malignancies but can result in immune mediated diarrhea and colitis (IDC). Currently, the …
malignancies but can result in immune mediated diarrhea and colitis (IDC). Currently, the …
Resumption of immune checkpoint inhibitor therapy after immune-mediated colitis
PURPOSE Immune checkpoint inhibitor (ICI) therapy often is suspended because of
immune-mediated diarrhea and colitis (IMDC). We examined the rate of and risk factors for …
immune-mediated diarrhea and colitis (IMDC). We examined the rate of and risk factors for …
[HTML][HTML] Immune checkpoint inhibition-related colitis: symptoms, endoscopic features, histology and response to management
MHG Foppen, EA Rozeman, S Van Wilpe, C Postma… - ESMO open, 2018 - Elsevier
Background Immune checkpoint inhibitors are successfully introduced as anticancer
treatment. However, they may induce severe immune-related adverse events (irAEs). One of …
treatment. However, they may induce severe immune-related adverse events (irAEs). One of …
Management of patients with immune checkpoint inhibitor-induced enterocolitis: a systematic review
M Collins, E Soularue, L Marthey… - Clinical gastroenterology …, 2020 - Elsevier
Immune checkpoint inhibitors (ICIs) have improved the treatment of several cancers. These
drugs increase T-cell activity and the antitumor immune response but also have immune …
drugs increase T-cell activity and the antitumor immune response but also have immune …
Gastrointestinal adverse events associated with immune checkpoint inhibitor therapy
Immunotherapy with checkpoint inhibitors has revolutionized cancer therapy and is now the
standard treatment for several different types of cancer, supported by favorable outcomes …
standard treatment for several different types of cancer, supported by favorable outcomes …
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