Concordance in pathogen identification at the upper and lower respiratory tract of children with severe pneumonia

H Wang, X Li, Y Zheng, LM Verhagen, J Gu, L Li… - BMC infectious …, 2023 - Springer
Background Nasopharyngeal swabs are taken to determine the causative agent of
community acquired pneumonia (CAP), while the reliability of upper respiratory tract …

Viral pathogen detection by metagenomics and pan-viral group polymerase chain reaction in children with pneumonia lacking identifiable etiology

R Schlaberg, K Queen, K Simmon… - The Journal of …, 2017 - academic.oup.com
Background. Community-acquired pneumonia (CAP) is a leading cause of pediatric
hospitalization. Pathogen identification fails in approximately 20% of children but is critical …

Approach to identifying causative pathogens of community-acquired pneumonia in children using culture, molecular, and serology tests

Y Mardian, A Menur Naysilla, D Lokida, H Farida… - Frontiers in …, 2021 - frontiersin.org
Determining the causative pathogen (s) of community-acquired pneumonia (CAP) in
children remains a challenge despite advances in diagnostic methods. Currently available …

Epidemiology and microbiological investigations of community-acquired pneumonia in children admitted at the emergency department of a university hospital

A Cantais, O Mory, S Pillet, PO Verhoeven… - Journal of clinical …, 2014 - Elsevier
Background The management of children with community-acquired pneumonia (CAP) is
largely influenced by the development of new molecular diagnostic tests that allow the …

Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

MU Bhuiyan, CC Blyth, R West, J Lang… - BMC pulmonary …, 2019 - Springer
Background Differentiating bacterial from viral pneumonia is important for guiding targeted
management and judicious use of antibiotics. We assessed if clinical characteristics and …

Clinical Evaluation of Metagenomic Next-Generation Sequencing for the detection of pathogens in BALF in severe community acquired pneumonia

Y Wei, T Zhang, Y Ma, J Yan, J Zhan, J Zheng… - Italian Journal of …, 2023 - Springer
Background Rapid and accurate identification of pathogens is very important for the
treatment of Severe community-acquired pneumonia (SCAP) in children. Metagenomic Next …

Epidemiologic, clinical, and serum markers may improve discrimination between bacterial and viral etiologies of childhood pneumonia

H Farida, R Triasih, D Lokida, Y Mardian… - Frontiers in …, 2023 - frontiersin.org
Background Discrimination of bacterial and viral etiologies of childhood community-acquired
pneumonia (CAP) is often challenging. Unnecessary antibiotic administration exposes …

Prevalence and clinical significance of common respiratory pathogens in the upper respiratory tract of children with community‐acquired pneumonia in Zunyi, China

X Li, W Zhang, S Yao, H Zha, B Huang… - Pediatric …, 2020 - Wiley Online Library
Purpose To estimate the prevalence of common respiratory pathogens among children with
community‐acquired pneumonia (CAP) in Zunyi City, Guizhou, China, and to assess …

Pathogen spectra in hospitalised and nonhospitalised children with community-acquired pneumonia

M Wetzke, K Schütz, MV Kopp… - ERJ Open …, 2023 - Eur Respiratory Soc
Background Paediatric community-acquired pneumonia (CAP) is a leading cause of
paediatric morbidity. However, particularly for outpatients with paediatric CAP, data on …

Clinical characteristics and etiology of community-acquired pneumonia in US children, 2015–2018

KW Yun, R Wallihan, A Desai, S Alter… - The Pediatric …, 2022 - journals.lww.com
Background: Pneumonia has a major impact on childhood health and health care costs. This
study was designed to obtain contemporary information on the clinical characteristics and …