[HTML][HTML] Nutrient sensor in the brain directs the action of the brain-gut axis in Drosophila

M Dus, JSY Lai, KM Gunapala, S Min, TD Tayler… - Neuron, 2015 - cell.com
Animals can detect and consume nutritive sugars without the influence of taste. However,
the identity of the taste-independent nutrient sensor and the mechanism by which animals …

[HTML][HTML] Periphery signals generated by Piezo-mediated stomach stretch and Neuromedin-mediated glucose load regulate the Drosophila brain nutrient sensor

Y Oh, JSY Lai, S Min, HW Huang, SD Liberles… - Neuron, 2021 - cell.com
Nutrient sensors allow animals to identify foods rich in specific nutrients. The Drosophila
nutrient sensor, diuretic hormone 44 (DH44) neurons, helps the fly to detect nutritive sugar …

[HTML][HTML] A post-ingestive amino acid sensor promotes food consumption in Drosophila

Z Yang, R Huang, X Fu, G Wang, W Qi, D Mao, Z Shi… - Cell research, 2018 - nature.com
Adequate protein intake is crucial for the survival and well-being of animals. How animals
assess prospective protein sources and ensure dietary amino acid intake plays a critical role …

[HTML][HTML] Pharyngeal sense organs drive robust sugar consumption in Drosophila

EE LeDue, YC Chen, AY Jung, A Dahanukar… - Nature …, 2015 - nature.com
The fly pharyngeal sense organs lie at the transition between external and internal nutrient-
sensing mechanisms. Here we investigate the function of pharyngeal sweet gustatory …

[HTML][HTML] A fructose receptor functions as a nutrient sensor in the Drosophila brain

T Miyamoto, J Slone, X Song, H Amrein - Cell, 2012 - cell.com
Internal nutrient sensors play important roles in feeding behavior, yet their molecular
structure and mechanism of action are poorly understood. Using Ca 2+ imaging and …

[HTML][HTML] Four GABAergic interneurons impose feeding restraint in Drosophila

AH Pool, P Kvello, K Mann, SK Cheung, MD Gordon… - Neuron, 2014 - cell.com
Feeding is dynamically regulated by the palatability of the food source and the physiological
needs of the animal. How consumption is controlled by external sensory cues and internal …

[HTML][HTML] A gut-derived hormone suppresses sugar appetite and regulates food choice in Drosophila

A Malita, O Kubrak, T Koyama, N Ahrentløv… - Nature …, 2022 - nature.com
Animals must adapt their dietary choices to meet their nutritional needs. How these needs
are detected and translated into nutrient-specific appetites that drive food-choice behaviours …

[HTML][HTML] Candidate Gustatory Interneurons Modulating Feeding Behavior in the Drosophila Brain

C Melcher, MJ Pankratz - PLoS biology, 2005 - journals.plos.org
Feeding is a fundamental activity of all animals that can be regulated by internal energy
status or external sensory signals. We have characterized a zinc finger transcription factor …

[HTML][HTML] Coupled sensing of hunger and thirst signals balances sugar and water consumption

N Jourjine, BC Mullaney, K Mann, K Scott - Cell, 2016 - cell.com
Hunger and thirst are ancient homeostatic drives for food and water consumption. Although
molecular and neural mechanisms underlying these drives are currently being uncovered …

A nutrient-specific gut hormone arbitrates between courtship and feeding

HH Lin, MC Kuang, I Hossain, Y Xuan, L Beebe… - Nature, 2022 - nature.com
Animals must set behavioural priority in a context-dependent manner and switch from one
behaviour to another at the appropriate moment,–. Here we probe the molecular and …