Background & Aims Alcoholic steatohepatitis (ASH) is the progressive form of alcoholic liver
disease and may lead to cirrhosis and hepatocellular carcinoma. We studied mouse models …

The cell death‐inducing DNA fragmentation factor alpha‐like effector c (CIDEC; also known
in rodents as FSP27 or fat‐specific protein 27) is a lipid droplet‐associated protein that …

Improved understanding of the molecular mechanisms responsible for the progression from
a “non-pathogenic” steatotic state to Non-Alcoholic Steatohepatitis is an important clinical …

FSP27 [cell death-inducing DFFA-like effector c (CIDEC) in humans] is a protein associated
with lipid droplets that downregulates the fatty acid oxidation (FAO) rate when it is …

Peroxisome proliferator-activated receptor γ (PPARγ) is induced in leptin-deficient (ob/ob)
mouse liver and is critical for the development of hepatic steatosis. The present study shows …

Hepatic fat-specific protein 27 [cell death-inducing DNA fragmentation effector protein C
(Cidec)/Fsp27] mRNA levels have been associated with hepatic lipid droplet extent under …

Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent complication of obesity, yet
cellular mechanisms that lead to its development are not well defined. Previously, we have …

Fat‐specific protein 27 (Fsp27) is a lipid droplet‐associated protein that promotes lipid
droplet (LD) growth and triglyceride (TG) storage in white adipocytes. Fsp27 is also highly …

White adipose tissue (WAT) functions as an energy reservoir where excess circulating fatty
acids are transported to WAT, converted to triglycerides, and stored as unilocular lipid …

Alcoholic liver disease (ALD) is associated with changes in the intestinal microbiota.
Functional consequences of alcohol‐associated dysbiosis are largely unknown. The aim of …