Synthesis, admetSAR predictions, DPPH radical scavenging activity, and potent anti-mycobacterial studies of hydrazones of substituted 4-(anilino methyl) …
Background: For the past several decades, the presence of tuberculosis (TB) is being
remarked as the most common infectious disease leading to mortality. Objective: Hydrazone …
remarked as the most common infectious disease leading to mortality. Objective: Hydrazone …
Design, characterization, computational studies, and pharmacological evaluation of substituted-N′-[(1E) substituted-phenylmethylidene]benzohydrazide analogs
S Bala, G Uppal, S Kamboj, V Saini… - Medicinal Chemistry …, 2013 - Springer
A series of substituted-N′-[(1E)-substituted-phenylmethylidene] benzohydrazide analogs
were synthesized and authenticated by TLC, UV–Visible, FTIR, and NMR spectroscopic …
were synthesized and authenticated by TLC, UV–Visible, FTIR, and NMR spectroscopic …
Synthesis, in silico and in vitro analysis of hydrazones as potential antituberculosis agents
BR Thorat, SN Mali, D Rani… - Current Computer-Aided …, 2021 - ingentaconnect.com
Tuberculosis (TB) is a major cause of mortality and illness as reported by the WHO in 2019.
The WHO report also mentioned the fact that about 10.0 million people fell ill with …
The WHO report also mentioned the fact that about 10.0 million people fell ill with …
Synthesis, pharmacokinetic and molecular docking studies of new benzohydrazide derivatives possessing anti-tubercular activity against Mycobacterium tuberculosis …
NH Lalavani, HR Gandhi, KA Bhensdadia… - Journal of Molecular …, 2022 - Elsevier
Tuberculosis scourge is at the most noteworthy danger, and it is urgent to characterize new
defenses against it. A new series of benzohydrazide derivatives containing benzylidene …
defenses against it. A new series of benzohydrazide derivatives containing benzylidene …
Synthesis, spectroscopic, in-vitro and computational analysis of hydrazones as potential antituberculosis agents:(part-I)
BR Thorat, D Rani, RS Yamgar… - … Chemistry & High …, 2020 - ingentaconnect.com
Background: Since the last few decades, the healthcare sector is facing the problem of the
development of multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis …
development of multidrug-resistant (MDR-TB) and extensively drug-resistant tuberculosis …
Ligand-based design and synthesis of N'-Benzylidene-3, 4-dimethoxybenzohydrazide derivatives as potential antimicrobial agents; evaluation by in vitro, in vivo, and …
RR Ezz Eldin, MA Saleh, MH Alotaibi… - Journal of Enzyme …, 2022 - Taylor & Francis
Herein, a series of N'-benzylidene-3, 4-dimethoxybenzohydrazide derivatives were
designed and synthesised to target the multidrug efflux pump (MATE). The antibacterial …
designed and synthesised to target the multidrug efflux pump (MATE). The antibacterial …
Synthesis, biological evaluation and 2D-QSAR study of halophenyl bis-hydrazones as antimicrobial and antitubercular agents
In continuation of our endeavor towards the development of potent and effective
antimicrobial agents, three series of halophenyl bis-hydrazones (14a–n, 16a–d, 17a and …
antimicrobial agents, three series of halophenyl bis-hydrazones (14a–n, 16a–d, 17a and …
Synthesis and anti-mycobacterium study on halo-substituted 2-aryl oxyacetohydrazones
Background: The treatment of multiple-drug-resistant tuberculosis (MDR-TB) with currently
available marketed drugs remains a global health concern. The cases of resistant …
available marketed drugs remains a global health concern. The cases of resistant …
Isonicotinoyl-butanoic acid hydrazone derivatives as anti-tubercular agents: In-silico studies, synthesis, spectral characterization and biological evaluation
MS Lone, MM Mubarak, SA Nabi, FR Wani… - Medicinal Chemistry …, 2023 - Springer
Abstract A series of novel 4-(2-isonicotinoylhydrazono)-4-aroylbutanoic acid derivatives (3a-
n) were designed, synthesized and characterized by 1H-NMR, 13C-NMR, and mass …
n) were designed, synthesized and characterized by 1H-NMR, 13C-NMR, and mass …
Design, synthesis and 2D QSAR study of novel pyridine and quinolone hydrazone derivatives as potential antimicrobial and antitubercular agents
The increased development of highly resistant bacterial strains and tuberculosis, constitute a
serious public health threat, highlighting the urgent need of novel antibacterial agents. In this …
serious public health threat, highlighting the urgent need of novel antibacterial agents. In this …