Electrical stimulation is an effective tool for mapping and altering brain connectivity, with
applications ranging from treating pharmacology-resistant neurological disorders to …

How does human brain stimulation result in lasting changes in cortical excitability?
Uncertainty on this question hinders the development of personalized brain stimulation …

Electrical stimulation of the brain has become a mainstay of fundamental neuroscience
research and an increasingly prevalent clinical therapy. Despite decades of use in basic …

The development of modern neuroscience tools is critical for deciphering brain circuit
organization and function. An important aspect for technical development is to enhance …

Local cortical circuit activity in vivo comprises a complex and flexible series of interactions
between excitatory and inhibitory neurons. Our understanding of the functional interactions …

During cortical circuit development in the mammalian brain, groups of excitatory neurons
that receive similar sensory information form microcircuits. However, cellular mechanisms …

Background Synaptic interactions between excitatory and inhibitory neocortical neurons are
important for mammalian sensory perception. Synaptic transmission between identified …

Background To dissect the intricate workings of neural circuits, it is essential to gain precise
control over subsets of neurons while retaining the ability to monitor larger-scale circuit …

Electrical stimulation has been used in animals and humans to study potential causal links
between neural activity and specific cognitive functions. Recently, it has found increasing …

Brain stimulation modulates the excitability of neural circuits and drives neuroplasticity.
While the local effects of stimulation have been an active area of investigation, the effects on …