Understanding the pathogenesis of occupational coal and silica dust-associated lung disease

KS Vanka, S Shukla, HM Gomez… - European …, 2022 - Eur Respiratory Soc
Workers in the mining and construction industries are at increased risk of respiratory and
other diseases as a result of being exposed to harmful levels of airborne particulate matter …

From coal mine dust to quartz: mechanisms of pulmonary pathogenicity

V Castranova - Inhalation Toxicology, 2000 - Taylor & Francis
Exposure to coal mine dust or crystalline silica can result in the initiation and progression of
interstitial lung disease. Pathogenesis is the consequence of damage to lung cells and …

Silicosis and coal workers' pneumoconiosis.

V Castranova, V Vallyathan - Environmental health perspectives, 2000 - ehp.niehs.nih.gov
Exposure to coal mine dust and/or crystalline silica results in pneumoconiosis with initiation
and progression of pulmonary fibrosis. This review presents characteristics of simple and …

Mechanistically identified suitable biomarkers of exposure, effect, and susceptibility for silicosis and coal-worker's pneumoconiosis: a comprehensive review

M Gulumian, PJA Borm, V Vallyathan… - Journal of Toxicology …, 2006 - Taylor & Francis
Clinical detection of silicosis is currently dependent on radiological and lung function
abnormalities, both late manifestations of disease. Markers of prediction and early detection …

Coal mine dust lung disease. New lessons from an old exposure

EL Petsonk, C Rose, R Cohen - American journal of respiratory and …, 2013 - atsjournals.org
Coal mining remains a sizable industry, with millions of working and retired coal miners
worldwide. This article provides an update on recent advances in the understanding of …

The impact of coal mine dust characteristics on pathways to respiratory harm: investigating the pneumoconiotic potency of coals

C Kamanzi, M Becker, M Jacobs, P Konečný… - Environmental …, 2023 - Springer
Exposure to dust from the mining environment has historically resulted in epidemic levels of
mortality and morbidity from pneumoconiotic diseases such as silicosis, coal workers' …

A systematic review of occupational exposure to coal dust and the risk of interstitial lung diseases

C Beer, HA Kolstad, K Søndergaard… - European Clinical …, 2017 - Taylor & Francis
Objective: Exposure to coal dust can cause interstitial lung disease (ILD), but whether this is
due to pure coal or to the contents of quartz in coal is less clear. Here, we systematically …

Coal mine dust lung disease in the modern era

JL Perret, B Plush, P Lachapelle, TSC Hinks… - …, 2017 - Wiley Online Library
ABSTRACT Coal workers' pneumoconiosis (CWP), as part of the spectrum of coal mine dust
lung disease (CMDLD), is a preventable but incurable lung disease that can be complicated …

Respiratory diseases caused by coal mine dust

AS Laney, DN Weissman - Journal of occupational and …, 2014 - journals.lww.com
Objective: To provide an update on respiratory diseases caused by coal mine dust. Methods:
This article presents the results of a literature review initially performed for an International …

Cytokines and cytokine network in silicosis and coal workers' pneumoconiosis

D Vanhee, P Gosset, A Boitelle… - European …, 1995 - Eur Respiratory Soc
The alveolar macrophage (AM) is a critically important cell playing a prominent role in lung
inflammation via the production of oxygen radicals, enzymes, arachidonic acid metabolites …