Tumor-infiltrating lymphocytes for adoptive cell therapy: recent advances, challenges, and future directions
JS Granhøj, A Witness Præst Jensen… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) is a highly
personalized type of cancer immunotherapy. TIL-based ACT exploits naturally occurring …
personalized type of cancer immunotherapy. TIL-based ACT exploits naturally occurring …
[HTML][HTML] Perspectives of tumor-infiltrating lymphocyte treatment in solid tumors
Tumor-infiltrating lymphocyte (TIL) therapy is a type of adoptive cellular therapy by
harvesting infiltrated lymphocytes from tumors, culturing and amplifying them in vitro and …
harvesting infiltrated lymphocytes from tumors, culturing and amplifying them in vitro and …
[HTML][HTML] Cell therapy with TILs: training and taming T cells to fight cancer
A Kumar, R Watkins, AE Vilgelm - Frontiers in immunology, 2021 - frontiersin.org
The rationale behind cancer immunotherapy is based on the unequivocal demonstration
that the immune system plays an important role in limiting cancer initiation and progression …
that the immune system plays an important role in limiting cancer initiation and progression …
[HTML][HTML] Adoptive T cell therapy for solid tumors: pathway to personalized standard of care
SS Qin, AD Melucci, AC Chacon, PA Prieto - Cells, 2021 - mdpi.com
Adoptive cell therapy (ACT) with tumor-infiltrating T cells (TILs) has emerged as a promising
therapy for the treatment of unresectable or metastatic solid tumors. One challenge to finding …
therapy for the treatment of unresectable or metastatic solid tumors. One challenge to finding …
Tumor-infiltrating lymphocyte therapy: addressing prevailing questions
LG Radvanyi - The Cancer Journal, 2015 - journals.lww.com
Autologous adoptive T-cell therapies have made tremendous strides over the last few years
with excitement currently being generated by technologies that can reprogram T-cell …
with excitement currently being generated by technologies that can reprogram T-cell …
Tumor-infiltrating lymphocyte therapy for melanoma: rationale and issues for further clinical development
GC Sim, J Chacon, C Haymaker, K Ritthipichai… - BioDrugs, 2014 - Springer
Cancer immunotherapy has become an important area for the future development of cancer
therapy; this includes T-cell-based therapies that involve adoptive transfer of autologous T …
therapy; this includes T-cell-based therapies that involve adoptive transfer of autologous T …
White paper on adoptive cell therapy for cancer with tumor-infiltrating lymphocytes: a report of the CTEP subcommittee on adoptive cell therapy
Adoptive T-cell therapy (ACT) using expanded autologous tumor-infiltrating lymphocytes
(TIL) and tumor antigen-specific T cell expanded from peripheral blood are complex but …
(TIL) and tumor antigen-specific T cell expanded from peripheral blood are complex but …
Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve …
IM Svane, EM Verdegaal - Cancer immunology, immunotherapy, 2014 - Springer
Adoptive cell therapy (ACT) based on autologous T cell derived either from tumor as tumor-
infiltrating lymphocytes (TILs) or from peripheral blood is developing as a key area of future …
infiltrating lymphocytes (TILs) or from peripheral blood is developing as a key area of future …
[HTML][HTML] Expansion and characterization of human melanoma tumor-infiltrating lymphocytes (TILs)
LT Nguyen, PH Yen, J Nie, N Liadis, D Ghazarian… - PloS one, 2010 - journals.plos.org
Background Various immunotherapeutic strategies for cancer are aimed at augmenting the
T cell response against tumor cells. Adoptive cell therapy (ACT), where T cells are …
T cell response against tumor cells. Adoptive cell therapy (ACT), where T cells are …
[HTML][HTML] Tumor infiltrating lymphocyte (TIL) therapy for solid tumor treatment: progressions and challenges
Simple Summary Over the past decade, cell-based immunotherapy has become a powerful
strategy in solid cancer therapy. Tumor-infiltrating lymphocytes (TILs) are a group of …
strategy in solid cancer therapy. Tumor-infiltrating lymphocytes (TILs) are a group of …