Nanobiotechnology-based delivery strategies: New frontiers in brain tumor targeted therapies

A Mangraviti, D Gullotti, B Tyler, H Brem - Journal of Controlled Release, 2016 - Elsevier
Despite recent technological advancements and promising preclinical experiments, brain
tumor patients are still met with limited treatment options. Some of the barriers to clinical …

[HTML][HTML] Emerging nano-carrier strategies for brain tumor drug delivery and considerations for clinical translation

DJ Lundy, H Nguyễn, PCH Hsieh - Pharmaceutics, 2021 - mdpi.com
Treatment of brain tumors is challenging since the blood–brain tumor barrier prevents
chemotherapy drugs from reaching the tumor site in sufficient concentrations …

Drug delivery and targeting to brain tumors: Considerations for crossing the blood-brain barrier

Y Omidi, N Kianinejad, Y Kwon… - Expert Review of Clinical …, 2021 - Taylor & Francis
Introduction: The blood-brain barrier (BBB) selectively impedes the transportation of drug
molecules into the brain, which makes the drug delivery and targeting of brain tumors very …

[HTML][HTML] Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

Noninvasive nanoparticle strategies for brain tumor targeting

C Sun, Y Ding, L Zhou, D Shi, L Sun, TJ Webster… - … , Biology and Medicine, 2017 - Elsevier
The blood–brain barrier (BBB) maintains the integrity and homeostasis of the central
nervous system (CNS) yet represents an intimidating hurdle for efficient drug delivery to …

Recent advances in nano delivery systems for blood-brain barrier (BBB) penetration and targeting of brain tumors

S Reddy, K Tatiparti, S Sau, AK Iyer - Drug Discovery Today, 2021 - Elsevier
Gliomas constitute about 80% of brain tumors and have a meager two-year survival rate.
The treatment options available are very few because of poor prognosis and a lack of …

Beyond the blood–brain barrier: facing new challenges and prospects of nanotechnology-mediated targeted delivery to the brain

M Kumar, P Sharma, R Maheshwari, M Tekade… - … -Based Targeted Drug …, 2018 - Elsevier
The blood–brain barrier (BBB) is a stealth barrier that protects the brain, and allows the entry
of only a select pool of compounds into the brain and functions towards the maintenance of …

Combinatorial therapeutic strategies for enhanced delivery of therapeutics to brain cancer cells through nanocarriers: current trends and future perspectives

X Wang, C Wu, S Liu, D Peng - Drug Delivery, 2022 - Taylor & Francis
Brain cancer is the most aggressive one among various cancers. It has a drastic impact on
people's lives because of the failure in treatment efficacy of the currently employed …

[图书][B] Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors

P Kesharwani, U Gupta - 2018 - books.google.com
Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain
anatomy and tumors and the progress and challenges in delivering drugs across the blood …

Nanotherapeutic systems for local treatment of brain tumors

RW Chakroun, P Zhang, R Lin… - Wiley …, 2018 - Wiley Online Library
Malignant brain tumor, including the most common type glioblastoma, are histologically
heterogeneous and invasive tumors known as the most devastating neoplasms with high …