[HTML][HTML] White matter changes and its relationship with clinical symptom in medication-naive first-episode early onset schizophrenia

J Cai, M Xie, L Zhao, X Li, S Liang, W Deng… - Asian Journal of …, 2023 - Elsevier
Previous studies have highlighted the role of white matter (WM) alterations as biomarkers of
the disease state and prognosis of schizophrenia. However, less is known about WM …

White matter microstructure in ultra-high risk and first episode schizophrenia: a prospective study

S Rigucci, G Santi, V Corigliano, A Imola… - Psychiatry Research …, 2016 - Elsevier
There is increasing evidence of white matter (WM) pathology in schizophrenia, but its role at
the very early stage of the disorder remains unclear. In an exploration of WM microstructure …

[HTML][HTML] Sex difference in association of symptoms and white matter deficits in first-episode and drug-naive schizophrenia

XE Lang, D Zhu, G Zhang, X Du, Q Jia, G Yin… - Translational …, 2018 - nature.com
Accumulating evidence shows that disruption of white matter (WM) may be involved in the
pathophysiology of schizophrenia, even at the onset of psychosis. However, very few studies …

Global white matter abnormalities in schizophrenia: a multisite diffusion tensor imaging study

T White, VA Magnotta, HJ Bockholt… - Schizophrenia …, 2011 - academic.oup.com
Background: Emerging evidence implicates white matter (WM) abnormalities in the
pathophysiology of schizophrenia. However, there is considerable heterogeneity in the …

Elucidation of shared and specific white matter findings underlying psychopathology clusters in schizophrenia

J Lim, R Chin, NF Ho, M Lam, MY Sum… - Asian Journal of …, 2017 - Elsevier
Background Schizophrenia is associated with diverse white matter (WM) brain
abnormalities. In this study, we sought to examine the WM microstructural findings which …

A longitudinal study investigating sub-threshold symptoms and white matter changes in individuals with an 'at risk mental state'(ARMS)

N Katagiri, C Pantelis, T Nemoto, A Zalesky, M Hori… - Schizophrenia …, 2015 - Elsevier
Background Evidence supports disruption in white matter (WM) connectivity in established
schizophrenia, however, it is unclear when these abnormalities occur during the course of …

Two patterns of white matter abnormalities in medication-naive patients with first-episode schizophrenia revealed by diffusion tensor imaging and cluster analysis

H Sun, S Lui, L Yao, W Deng, Y Xiao, W Zhang… - JAMA …, 2015 - jamanetwork.com
Importance Accumulating evidence supports the hypothesis that cerebral white matter
abnormalities are involved in the pathophysiology of schizophrenia; however, findings from …

White matter changes in first episode psychosis and their relation to the size of sample studied: a DTI study

T Melicher, J Horacek, J Hlinka, F Spaniel… - Schizophrenia …, 2015 - Elsevier
Background White matter abnormality has been recently proposed as a pathophysiological
feature of schizophrenia (SZ). However, most of the data available has been gathered from …

[HTML][HTML] White matter deficits in first episode schizophrenia: an activation likelihood estimation meta-analysis

L Yao, S Lui, Y Liao, MY Du, N Hu, JA Thomas… - Progress in Neuro …, 2013 - Elsevier
Background Diffusion tensor imaging (DTI) has been widely used in psychiatric research
and has provided evidence of white matter abnormalities in first episode schizophrenia …

[HTML][HTML] Relationship between white matter alterations and pathophysiological symptoms in patients with ultra-high risk of psychosis, first-episode, and chronic …

K Waszczuk, E Tyburski, K Rek-Owodziń, P Plichta… - Brain Sciences, 2022 - mdpi.com
Some symptoms of schizophrenia might be present before full-blown psychosis, so white
matter changes must be studied both in individuals with emerging psychosis and chronic …