TRPV4: molecular conductor of a diverse orchestra
Transient receptor potential vanilloid type 4 (TRPV4) is a calcium-permeable nonselective
cation channel, originally described in 2000 by research teams led by Schultz (Nat Cell Biol …
cation channel, originally described in 2000 by research teams led by Schultz (Nat Cell Biol …
The vanilloid transient receptor potential channel TRPV4: from structure to disease
W Everaerts, B Nilius, G Owsianik - Progress in biophysics and molecular …, 2010 - Elsevier
The Transient Receptor Potential Vanilloid 4 channel, TRPV4, is a Ca2+ and Mg2+
permeable non-selective cation channel involved in many different cellular functions. It is …
permeable non-selective cation channel involved in many different cellular functions. It is …
The TRPV4 channel: structure-function relationship and promiscuous gating behaviour
Transient receptor potential (TRP) channels provide an enormous variability of Ca 2+ influx
mechanisms triggered by a wide range of stimuli. In this review, we discuss the activation …
mechanisms triggered by a wide range of stimuli. In this review, we discuss the activation …
[HTML][HTML] TRPV1: structure, endogenous agonists, and mechanisms
M Benítez-Angeles, SL Morales-Lázaro… - International journal of …, 2020 - mdpi.com
The Transient Receptor Potential Vanilloid 1 (TRPV1) channel is a polymodal protein with
functions widely linked to the generation of pain. Several agonists of exogenous and …
functions widely linked to the generation of pain. Several agonists of exogenous and …
[HTML][HTML] TRPing to the point of clarity: understanding the function of the complex TRPV4 ion channel
TL Toft-Bertelsen, N MacAulay - Cells, 2021 - mdpi.com
The transient receptor potential vanilloid 4 channel (TRPV4) belongs to the mammalian TRP
superfamily of cation channels. TRPV4 is ubiquitously expressed, activated by a disparate …
superfamily of cation channels. TRPV4 is ubiquitously expressed, activated by a disparate …
PI3-kinase promotes TRPV2 activity independently of channel translocation to the plasma membrane
Cellular or chemical activators for most transient receptor potential channels of the vanilloid
subfamily (TRPV) have been identified in recent years. A remarkable exception to this is …
subfamily (TRPV) have been identified in recent years. A remarkable exception to this is …
[HTML][HTML] Activation of the TRPV4 ion channel is enhanced by phosphorylation
HC Fan, X Zhang, PA McNaughton - Journal of Biological Chemistry, 2009 - ASBMB
The TRPV4 (transient receptor potential vanilloid 4) ion channel, a member of the vanilloid
subfamily of the transient receptor potential channels, is activated by membrane stretch, by …
subfamily of the transient receptor potential channels, is activated by membrane stretch, by …
What do we know about the transient receptor potential vanilloid 2 (TRPV 2) ion channel?
A Perálvarez‐Marín, P Doñate‐Macian… - The FEBS …, 2013 - Wiley Online Library
Transient receptor potential (TRP) ion channels are emerging as a new set of membrane
proteins involved in a vast array of cellular processes and regulated by a large number of …
proteins involved in a vast array of cellular processes and regulated by a large number of …
[HTML][HTML] An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels
Transient receptor potential vanilloid 1 (TRPV1), or vanilloid receptor 1, is the founding
member of the vanilloid type of TRP superfamily of nonselective cation channels. TRPV1 is …
member of the vanilloid type of TRP superfamily of nonselective cation channels. TRPV1 is …
TRPV1 shows dynamic ionic selectivity during agonist stimulation
Transient receptor potential vanilloid 1 (TRPV1) is an ion channel that is gated by noxious
heat, capsaicin and other diverse stimuli. It is a nonselective cation channel that prefers …
heat, capsaicin and other diverse stimuli. It is a nonselective cation channel that prefers …