[HTML][HTML] Prurigo Nodularis: Pathogenesis and the Horizon of Potential Therapeutics

HJ Yook, JH Lee - International Journal of Molecular Sciences, 2024 - mdpi.com
Chronic pruritus that lasts for over 6 weeks can present in various forms, like papules,
nodules, and plaque types, with prurigo nodularis (PN) being the most prevalent. The …

[HTML][HTML] Chronic nodular prurigo: an update on the pathogenesis and treatment

LS Wong, YT Yen - International Journal of Molecular Sciences, 2022 - mdpi.com
Chronic nodular prurigo (CNPG) is a recalcitrant chronic itchy disorder that affects the quality
of life. It can be triggered by multiple etiologies, such as atopic dermatitis, diabetes, and …

[HTML][HTML] Molecular mechanisms of pruritus in prurigo nodularis

Y Shao, D Wang, Y Zhu, Z Xiao, T Jin, L Peng… - Frontiers in …, 2023 - frontiersin.org
Pruritus is the most common symptom of dermatological disorders, and prurigo nodularis
(PN) is notorious for intractable and severe itching. Conventional treatments often yield …

Prurigo nodularis management

A Tsianakas, C Zeidler, S Ständer - Itch-Management in Clinical …, 2016 - karger.com
Characterized by the clinical presentation of individual to multiple symmetrically distributed,
hyperkeratotic, and intensely itchy papules and nodules, prurigo nodularis (PN) is a rare …

Treatment-resistant prurigo nodularis: challenges and solutions

EH Kowalski, D Kneiber, M Valdebran… - Clinical, cosmetic and …, 2019 - Taylor & Francis
Prurigo nodualris (PN) is a chronic condition with highly pruritic, hyperkeratotic papules or
nodules arising in the setting of chronic pruritus. While PN may serve as a phenotypic …

The pathogenesis of Prurigo nodularis–'Super‐Itch'in exploration

C Zeidler, S Ständer - European Journal of Pain, 2016 - Wiley Online Library
Prurigo nodularis (PN) is characterized by multiple hyperkeratotic nodules, papules and the
presence of intensive pruritus. This leads to an impaired quality of life and high burden due …

Prurigo nodularis: new insights into pathogenesis and novel therapeutics

V Liao, HL Cornman, E Ma… - British Journal of …, 2024 - academic.oup.com
Prurigo nodularis (PN) is an inflammatory skin condition characterized by intensely pruritic
nodules on the skin. Patients with PN suffer from an intractable itch–scratch cycle leading to …

Prurigo nodularis: review and emerging treatments.

M Leis, P Fleming, CW Lynde - Skin Therapy Letter, 2021 - europepmc.org
Prurigo nodularis (PN) is a chronic, recalcitrant inflammatory skin condition characterized by
the presence of pruritic nodules. The exact pathogenesis of the disease is unknown …

INDIVIDUAL ARTICLE: Prurigo Nodularis: Current Clinicopathologic Overview and Psychodermatological Perspectives

NT Issa, H Riva, M Jafferany - Journal of drugs in …, 2023 - pubmed.ncbi.nlm.nih.gov
Prurigo nodularis (PN) is a quintessential neurocutaneous condition characterized by neural
sensitization and intractable itch leading to intense scratching. This causes the formation of …

[HTML][HTML] Chronic prurigo including prurigo nodularis: new insights and treatments

S Müller, C Zeidler, S Ständer - American Journal of Clinical Dermatology, 2024 - Springer
Chronic prurigo (CPG) is a neuroinflammatory, fibrotic dermatosis that is defined by the
presence of chronic pruritus (itch lasting longer than 6 weeks), scratch-associated …