Right versus left colon cancer biology: integrating the consensus molecular subtypes

MS Lee, DG Menter, S Kopetz - Journal of the National Comprehensive …, 2017 - jnccn.org
Although clinical management of colon cancer generally has not accounted for the primary
tumor site, left-sided and right-sided colon cancers harbor different clinical and biologic …

[HTML][HTML] Different treatment strategies and molecular features between right-sided and left-sided colon cancers

H Shen, J Yang, Q Huang, MJ Jiang… - World journal of …, 2015 - ncbi.nlm.nih.gov
The colon is derived from the embryological midgut and hindgut separately, with the right
colon and left colon having different features with regards to both anatomical and …

[HTML][HTML] Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO. 17

SY Brulé, DJ Jonker, CS Karapetis… - European journal of …, 2015 - Elsevier
Background Right-and left-sided colon cancers (RC, LC) differ with respect to biology,
pathology and epidemiology. Previous data suggest a mortality difference between RC and …

Difference between right-sided and left-sided colorectal cancers: from embryology to molecular subtype

SY Yang, MS Cho, NK Kim - Expert review of anticancer therapy, 2018 - Taylor & Francis
Introduction: Colorectal cancer is one of the most common malignancies in the world, and it
exhibits differences in incidence, pathogenesis, molecular pathways, and outcome …

[HTML][HTML] Differences regarding the molecular features and gut microbiota between right and left colon cancer

K Kim, EJT Castro, H Shim, JVG Advincula… - Annals of …, 2018 - ncbi.nlm.nih.gov
For many years, developmental and physiological differences have been known to exist
between anatomic segments of the colorectum. Because of different outcomes, prognoses …

[HTML][HTML] Difference between left-sided and right-sided colorectal cancer: a focused review of literature

B Baran, NM Ozupek, NY Tetik, E Acar… - Gastroenterology …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer is the third most common cancer worldwide with a high mortality rate at
the advanced stages. However, colorectal cancer is not a single type of tumor; its …

Right‐and left‐sided colorectal cancers respond differently to cetuximab

F Wang, L Bai, TS Liu, YY Yu, MM He… - Cancer …, 2015 - Wiley Online Library
Introduction Right‐sided colon cancer (RSCC) and left‐sided colorectal cancer (LSCRC)
differ with respect to their biology and genomic patterns. This study aimed to examine …

[HTML][HTML] Comparative molecular analyses of left-sided colon, right-sided colon, and rectal cancers

ME Salem, BA Weinberg, J Xiu, WS El-Deiry… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Tumor sidedness has emerged as an important prognostic and predictive factor in the
treatment of colorectal cancer. Recent studies demonstrate that patients with advanced right …

[HTML][HTML] Right and left-sided colon cancers-specificity of molecular mechanisms in tumorigenesis and progression

K Mukund, N Syulyukina, S Ramamoorthy… - BMC cancer, 2020 - Springer
Background Given the differences in embryonic origin, vascular and nervous supplies,
microbiotic burden, and main physiological functions of left and right colons, tumor location …

[HTML][HTML] Better survival in right-sided versus left-sided stage I-III colon cancer patients

R Warschkow, MC Sulz, L Marti, I Tarantino… - BMC cancer, 2016 - Springer
Background The distinction between right-sided and left-sided colon cancer has recently
received considerable attention due to differences regarding underlying genetic mutations …