The interictal suppression hypothesis in focal epilepsy: network-level supporting evidence
Why are people with focal epilepsy not continuously having seizures? Previous neuronal
signalling work has implicated gamma-aminobutyric acid balance as integral to seizure …
signalling work has implicated gamma-aminobutyric acid balance as integral to seizure …
Brain network organization in focal epilepsy: a systematic review and meta-analysis
E Van Diessen, WJEM Zweiphenning, FE Jansen… - PloS one, 2014 - journals.plos.org
Normal brain functioning is presumed to depend upon interacting regions within large-scale
neuronal networks. Increasing evidence exists that interictal network alterations in focal …
neuronal networks. Increasing evidence exists that interictal network alterations in focal …
[HTML][HTML] High interictal connectivity within the resection zone is associated with favorable post-surgical outcomes in focal epilepsy patients
Patients with drug-resistant focal epilepsy are often candidates for invasive surgical
therapies. In these patients, it is necessary to accurately localize seizure generators to …
therapies. In these patients, it is necessary to accurately localize seizure generators to …
Regional and global connectivity disturbances in focal epilepsy, related neurocognitive sequelae, and potential mechanistic underpinnings
Epilepsy is among the most common brain network disorders, and it is associated with
substantial morbidity and increased mortality. Although focal epilepsy was traditionally …
substantial morbidity and increased mortality. Although focal epilepsy was traditionally …
Seizure‐onset regions demonstrate high inward directed connectivity during resting‐state: An SEEG study in focal epilepsy
S Narasimhan, KB Kundassery, K Gupta… - …, 2020 - Wiley Online Library
Objective In patients with medically refractory focal epilepsy, stereotactic‐
electroencephalography (SEEG) can aid in localizing epileptogenic regions for surgical …
electroencephalography (SEEG) can aid in localizing epileptogenic regions for surgical …
Emergent network topology at seizure onset in humans
Epilepsy–the world's most common serious brain disorder–is defined by recurrent
unprovoked seizures that result from complex interactions between distributed neural …
unprovoked seizures that result from complex interactions between distributed neural …
Initiation, propagation, and termination of partial (focal) seizures
M de Curtis, M Avoli - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The neurophysiological patterns that correlate with partial (focal) seizures are well defined in
humans by standard electroencephalogram (EEG) and presurgical depth electrode …
humans by standard electroencephalogram (EEG) and presurgical depth electrode …
Characterization of functional and structural integrity in experimental focal epilepsy: reduced network efficiency coincides with white matter changes
WM Otte, RM Dijkhuizen, MPA van Meer… - PLoS …, 2012 - journals.plos.org
Background Although focal epilepsies are increasingly recognized to affect multiple and
remote neural systems, the underlying spatiotemporal pattern and the relationships between …
remote neural systems, the underlying spatiotemporal pattern and the relationships between …
[HTML][HTML] Structural and effective connectivity in focal epilepsy
Patients with medically-refractory focal epilepsy may be candidates for neurosurgery and
some may require placement of intracranial EEG electrodes to localise seizure onset …
some may require placement of intracranial EEG electrodes to localise seizure onset …
Graph analysis of epileptogenic networks in human partial epilepsy
Purpose: The current gold standard for the localization of the cortical regions responsible for
the initiation and propagation of the ictal activity is through the use of invasive …
the initiation and propagation of the ictal activity is through the use of invasive …