[HTML][HTML] COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm
Sterol regulatory element binding protein-2 (SREBP-2) is activated by cytokines or
pathogen, such as virus or bacteria, but its association with diminished cholesterol levels in …
pathogen, such as virus or bacteria, but its association with diminished cholesterol levels in …
[HTML][HTML] Possible mechanisms of cholesterol elevation aggravating COVID-19
Y Tang, L Hu, Y Liu, B Zhou, X Qin, J Ye… - … journal of medical …, 2021 - ncbi.nlm.nih.gov
Importance: Despite the availability of a vaccine against the severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2), humans will have to live with this virus and the after …
syndrome-coronavirus-2 (SARS-CoV-2), humans will have to live with this virus and the after …
[HTML][HTML] Simvastatin downregulates the SARS-CoV-2-induced inflammatory response and impairs viral infection through disruption of lipid rafts
Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical …
[HTML][HTML] HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry
C Wei, L Wan, Q Yan, X Wang, J Zhang, X Yang… - Nature …, 2020 - nature.com
Responsible for the ongoing coronavirus disease 19 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through binding of the …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through binding of the …
[HTML][HTML] Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19
M Caterino, M Gelzo, S Sol, R Fedele, A Annunziata… - Scientific reports, 2021 - nature.com
In recent months, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 …
syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 …
[HTML][HTML] Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry
SN Palacios-Rápalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …
[HTML][HTML] COVID-19: direct and indirect mechanisms of statins
A Pawlos, M Niedzielski, P Gorzelak-Pabiś… - International Journal of …, 2021 - mdpi.com
The virus responsible for the current COVID-19 pandemic is severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2): a new virus with high infectivity and moderate …
syndrome coronavirus 2 (SARS-CoV-2): a new virus with high infectivity and moderate …
Plasma phospholipids: a promising simple biochemical parameter to evaluate COVID-19 infection severity
MA Hussein, NEM Ismail… - … and Biology Insights, 2021 - journals.sagepub.com
Background: Coronavirus-19 (COVID-19) pandemic is a worldwide public health problem
that has been known in China since December 25, 2019. Phospholipids are structural …
that has been known in China since December 25, 2019. Phospholipids are structural …
[HTML][HTML] SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling
F Li, J Li, PH Wang, N Yang, J Huang, J Ou, T Xu… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection-
induced inflammatory responses are largely responsible for the death of novel coronavirus …
induced inflammatory responses are largely responsible for the death of novel coronavirus …
Disrupted resolution mechanisms favor altered phagocyte responses in COVID-19
DS Koenis, I Beegun, CC Jouvene, GA Aguirre… - Circulation …, 2021 - Am Heart Assoc
Rationale: Resolution mechanisms are central in both the maintenance of homeostasis and
the return to catabasis following tissue injury and infections. Among the proresolving …
the return to catabasis following tissue injury and infections. Among the proresolving …