Context Pituitary adenoma (PA) is a common intracranial tumor. The evidence indicates that
the tumor immune microenvironment (TIME) is associated with PA and that the intestinal …

Pituitary adenoma (PA) includes invasive pituitary adenoma (IPA) and noninvasive pituitary
adenoma (NIPA), which are associated with the endocrine system. The gut microbiome …

Human papillomavirus (HPV) is the most common sexually transmitted pathogen worldwide
and the major risk factor for cervical cancer. According to our previous study, antitumor …

Purposes Immunotherapies for solid tumor are gaining traction in the clinic, however, the
immunological landscape of pituitary adenomas (PAs) is not well defined. In the present …

Prior study has demonstrated that gut microbiota at the genus level is significantly altered in
patients with growth hormone (GH)-secreting pituitary adenoma (GHPA). Yet, no studies …

Background Although immunotherapy works well in glioblastoma (GBM) preclinical mouse
models, the therapy has not demonstrated efficacy in humans. To address this anomaly, we …

The gut microbiome has been shown to influence the response of tumors to anti–PD-1
(programmed cell death–1) immunotherapy in preclinical mouse models and observational …

The gut-brain axis has paved our way in understanding varieties of disease. The gut
microbiota especially the bacterial population plays critical roles in immune system …

Purpose Bacteria have been observed in the tumor environment for decades and have been
demonstrated to play important roles in the pathogenesis and development of several …

Abstract Background Pituitary neuroendocrine tumors (PitNETs) are common gland
neoplasms demonstrating distinctive transcription factors. Although the role of immune cells …