Dual functionalized chitosan based composite hydrogel for haemostatic efficacy and adhesive property

G Singh, A Nayal, S Malhotra, V Koul - Carbohydrate polymers, 2020 - Elsevier
The objective of this study was to devise a dual functionalized chitosan based hydrogel
dressing to control haemorrhage/bleeding. The haemostatic hydrogel was formulated by …

Vasoconstrictor and coagulation activator entrapped chitosan based composite hydrogel for rapid bleeding control

MN Sundaram, U Mony, PK Varma… - Carbohydrate Polymers, 2021 - Elsevier
Chitosan (Cs) as a hemostatic agent has been in use to control hemorrage. Composite
hydrogel formed by entrapment of vasoconstrictor-potassium aluminium sulfate (0.25% PA) …

[HTML][HTML] A chitosan based multimodal “soft” hydrogel for rapid hemostasis of non-compressible hemorrhages and its mode of action

G Patil, R Pawar, S Jadhav, V Ghormade - … Polymer Technologies and …, 2022 - Elsevier
Uncontrolled hemorrhages during accidents or surgery require non-compressible dressings
to halt bleeding and avoid damage to soft tissue and organs. Here, we report the synthesis …

Chitosan-based multifunctional flexible hemostatic bio-hydrogel

F Song, Y Kong, C Shao, Y Cheng, J Lu, Y Tao, J Du… - Acta biomaterialia, 2021 - Elsevier
Realizing the potential application of chitosan as an effective biomedical hemostatic agent
has become an emerging research hotspot. However, fabricating a flexible chitosan-based …

Injectable chitosan-nano bioglass composite hemostatic hydrogel for effective bleeding control

MN Sundaram, S Amirthalingam, U Mony… - International journal of …, 2019 - Elsevier
Effective bleeding control is a major concern in trauma and major surgeries. Chitosan (Ch)
as hemostatic agent has been widely used and when applied at the site of injury it acts by …

Cytotoxicity and hemostatic activity of chitosan/carrageenan composite wound healing dressing for traumatic hemorrhage

SS Biranje, PV Madiwale, KC Patankar, R Chhabra… - Carbohydrate …, 2020 - Elsevier
Hemorrhage remains a big threat to trauma patients, especially in combat fields. Therefore,
we formulated a biocompatible and biopolymer based chitosan/carrageenan composite …

A review on recent advances in chitosan based composite for hemostatic dressings

MA Khan, M Mujahid - International journal of biological macromolecules, 2019 - Elsevier
High mortality rate in potentially survivable casualties due to severe hemorrhage is a major
challenge in today's battlefield because technological advancements have revolutionized …

Chitosan-based hemostatic hydrogels: The concept, mechanism, application, and prospects

P Fan, Y Zeng, D Zaldivar-Silva, L Agüero, S Wang - Molecules, 2023 - mdpi.com
The design of new hemostatic materials to mitigate uncontrolled bleeding in emergencies is
challenging. Chitosan-based hemostatic hydrogels have frequently been used for …

Fabrication of hydroxypropyl chitosan/soy protein isolate hydrogel for effective hemorrhage control

Y Zhao, A Xiao, P Wu, F Chen, Q Zhang… - … Engineering Part A, 2021 - liebertpub.com
Hemostatic materials are increasingly important in civilian and military clinics. In this work, a
hydrogel was fabricated from hydroxypropyl chitosan (HPCS) and soy protein isolate (SPI) …

New injectable chitosan-hyaluronic acid based hydrogels for hemostasis and wound healing

H Weng, W Jia, M Li, Z Chen - Carbohydrate polymers, 2022 - Elsevier
It is a challenge to develop hemostatic and wound dressings that are used for irregular
shape and deep wound. Herein, a series of novel N-succinyl chitosan-oxidized hyaluronic …