OBJECTIVE: Epidemiologic studies support an association between diet and the incidence
of colorectal cancer. Butyrate, a short-chain fatty acid present in dietary fiber and dairy …

Butyrate is a potent anticarcinogenic compound against colon cancer cells in vitro. However,
its rapid metabolism is hypothesized to limit its anticancer benefits in colonic epithelial cells …

Butyrate is produced in the colon of mammals as a result of microbial fermentation of dietary
fiber, undigested starch, and proteins (Rombeau 1990). Butyrate may be an important …

Butyrate, the four‐carbon fatty acid, is formed in the human colon by bacterial fermentation of
carbohydrates (including dietary fiber), and putatively suppresses colorectal cancer (CRC) …

Butyrate is produced in the colon by fermentation of dietary fibre and induces apoptosis in
colon adenoma and cancer cell lines, which may contribute to the protective effect of a high …

Dietary fiber has been suggested to suppress colorectal cancer development, although the
mechanisms contributing to this beneficial effect remain elusive. Butyrate, a fermentation …

Epidemiological studies have linked dietary fiber to the prevention of human colorectal
cancer and suggest that short chain fatty acids such as butyric acid, which is produced by …

Colo-rectal cancer is a major health problem in industrialized countries and the high
incidence has been linked with the diet (Burkitt, 1971). The colonic epithelium is in direct …

Epidemiological evidence suggests that a high intake of resistant starch and NSP protects
against colo-rectal cancer. The mechanisms underlying this protection are thought to be …

Butyric acid is a slightly volatile, water-soluble, 4-carbon carboxylic acid. Bacterial
fermentation of certain polysaccharides in the large intestine produces millimolar amounts of …