Objective: Imaging studies of major depressive disorder have reported structural and
functional abnormalities in a variety of spatially diverse brain regions. Quantitative meta …

Abnormalities in functional limbic–anterior cingulate–prefrontal circuits associated with
emotional reactivity, evaluation and regulation have been implicated in the pathophysiology …

Background Functional and anatomical deficits have been involved in the neurobiology of
major depressive disorder (MDD). However, no study has ever been conducted to examine …

Objective: Functional neuroimaging investigations of major depressive disorder can
advance both the neural theory and treatment of this debilitating illness. Inconsistency of …

Background Because brain morphological abnormalities in major depressive disorder
(MDD) may be modulated by medication and episodes, previous meta-analyses of voxel …

Background Current practice for selecting pharmacological and non-pharmacological
antidepressant treatments has yielded low response and remission rates in Major …

BACKGROUND: Depression has a lifetime prevalence of up to 20%. Neuroimaging methods
have revealed various structural and functional changes that occur in a human brain during …

The pattern of structural brain alterations associated with major depressive disorder (MDD)
remains unresolved. This is in part due to small sample sizes of neuroimaging studies …

BackgroundStudies investigating structural brain abnormalities in depression have typically
employed a categorical rather than dimensional approach to depression [ie comparing …

The growth of the literature about neuroimaging of major depressive disorder (MDD) over
the last several decades has contributed to the progress in recognizing precise brain areas …