Dihydropyridine preparation and application in the synthesis of pyridine derivatives

DL Comins, K Higuchi, DW Young - Advances in Heterocyclic Chemistry, 2013 - Elsevier
The preparation and application of dihydropyridines continue to attract considerable interest
in organic synthesis and medicinal chemistry. The biological activities and synthetic utility of …

Developments in the Synthesis of 1, 2-Dihydropyridines

EMP Silva, PAMM Varandas, AMS Silva - Synthesis, 2013 - thieme-connect.com
This review provides a comprehensive compilation of available literature concerning the
synthesis of 1, 2-dihydropyridines. The most important recent developments and concepts …

An efficient large-scale synthesis of alkyl 5-hydroxy-pyridin-and pyrimidin-2-yl acetate

R Morgentin, F Jung, M Lamorlette, M Maudet… - Tetrahedron, 2009 - Elsevier
The synthesis of methyl 2-(5-hydroxy-3-methoxypyridin-2-yl) acetate and alkyl 2-(5-
hydroxypyrimidin-2-yl) acetate is described. Methodology for an efficient access to 5-hydroxy …

An improved and efficient synthesis of 2-substituted 1, 4-dihydropyridine derivatives via regiospecific bromination

I Sircar, KR Anderson, L Bonadies - Tetrahedron letters, 1988 - Elsevier
EthWd w Page 1 Tetrahedron Letters,Vol.29,No.S2,pp 6835-6838,1988 0040-4039/88
$3.00 + .OO Printed in Great Britain Peraamon Press plc AN IMPROVED AND EFFICIENT …

Synthesis of 4‐alkyl‐3‐pyridinols from 3‐benzyloxypyridine

DL Comins, ED Stroud - Journal of heterocyclic chemistry, 1985 - Wiley Online Library
The addition of Grignard reagents to the 1‐phenoxycarbonyl salt of 3‐benzyloxypyridine and
a catalytic amount of cuprous iodide afforded 4‐alkyl‐3‐benzyloxy‐1‐phenoxycarbonyl‐1, 4 …

An Overview of Synthesis and Biological Activity of Dihydropyrimidine Derivatives.

AC Dudhe, R Dudhe, O Porwal… - Mini Reviews in Medicinal …, 2022 - europepmc.org
Dihydropyrimidine derivatives are the most important scaffolds due to structural similarities
with natural products; it is a heterocyclic compound. The chemistry of Dihydropyrimidine is a …

Regioselective Synthesis of N-Alkyl Pyridones

WR Bowman, CF Bridge - Synthetic communications, 1999 - Taylor & Francis
Regioselective Synthesis of <italic>N</italic>-Alkyl Pyridones Page 1 SYNTHETIC
COMMUNICATIONS, 29(22), 405 14059 (1999) REGIOSELECTIVE SYNTHESIS OF N-ALKYL …

[引用][C] Synthesis of 1, 4-dihydropyridines by cyclocondensation reactions

A Sausiņš, G Duburs - Heterocycles, 1988 - elibrary.ru
This review surveys the latest developments pertaining to the preparation of 1, 4-
dihydropyridines using Hantzsch synthesis and other cyclocondensation reactions.© 1988.

Regioselective synthesis of 4-alkylpyridines via 1, 4-dihydropyridine derivatives from pyridine

K Akiba, Y Iseki, M Wada - Tetrahedron Letters, 1982 - Elsevier
Abstract N-Ethoxycarbonylpyridinium chloride (1) reacted with RCu· BF 3 at 4-position with
almost complete regioselectivity (better than 99%) to afford the corresponding 1, 4 …

General synthesis of substituted 1, 2-dihydropyridines

D Tejedor, L Cotos, G Mendez-Abt… - The Journal of Organic …, 2014 - ACS Publications
A general and practical metal-free protocol for the synthesis of 1, 2-dihydropyridines with
wide structural/functional diversity at the ring and featuring mono, double, or spiro …