Locus coeruleus
The locus coeruleus (LC, Lat.“blue spot”) is a heavily pigmented nucleus located in the
dorsal wall of the rostral pons in the lateral floor of the fourth ventricle (Figure 12.1). The LC …
dorsal wall of the rostral pons in the lateral floor of the fourth ventricle (Figure 12.1). The LC …
Heterogeneous organization of the locus coeruleus projections to prefrontal and motor cortices
DJ Chandler, WJ Gao… - Proceedings of the …, 2014 - National Acad Sciences
The brainstem nucleus locus coeruleus (LC) is the primary source of norepinephrine (NE) to
the mammalian neocortex. It is believed to operate as a homogeneous syncytium of …
the mammalian neocortex. It is believed to operate as a homogeneous syncytium of …
Redefining noradrenergic neuromodulation of behavior: impacts of a modular locus coeruleus architecture
DJ Chandler, P Jensen, JG McCall… - Journal of …, 2019 - Soc Neuroscience
The locus coeruleus (LC) is a seemingly singular and compact neuromodulatory nucleus
that is a prominent component of disparate theories of brain function due to its broad …
that is a prominent component of disparate theories of brain function due to its broad …
Locus coeruleus: a new look at the blue spot
The locus coeruleus (LC), or 'blue spot', is a small nucleus located deep in the brainstem
that provides the far-reaching noradrenergic neurotransmitter system of the brain. This …
that provides the far-reaching noradrenergic neurotransmitter system of the brain. This …
Locus coeruleus: from global projection system to adaptive regulation of behavior
G Aston-Jones, B Waterhouse - Brain research, 2016 - Elsevier
The brainstem nucleus locus coeruleus (LC) is a major source of norepinephrine (NE)
projections throughout the CNS. This important property was masked in very early studies by …
projections throughout the CNS. This important property was masked in very early studies by …
Cellular composition and circuit organization of the locus coeruleus of adult mice
A McKinney, M Hu, A Hoskins, A Mohammadyar… - Elife, 2023 - elifesciences.org
The locus coeruleus (LC) houses the vast majority of noradrenergic neurons in the brain and
regulates many fundamental functions, including fight and flight response, attention control …
regulates many fundamental functions, including fight and flight response, attention control …
Organization of the locus coeruleus-norepinephrine system
LA Schwarz, L Luo - Current Biology, 2015 - cell.com
The release of the neurotransmitter norepinephrine throughout the mammalian brain is
important for modulating attention, arousal, and cognition during many behaviors …
important for modulating attention, arousal, and cognition during many behaviors …
Pre-locus coeruleus neurons in rat and mouse
S Gasparini, JM Resch, AM Gore… - American Journal …, 2021 - journals.physiology.org
Previously, we identified a population of neurons in the hindbrain tegmentum, bordering the
locus coeruleus (LC). We named this population the pre-locus coeruleus (pre-LC) because …
locus coeruleus (LC). We named this population the pre-locus coeruleus (pre-LC) because …
Two Subpopulations of Noradrenergic Neurons in the Locus Coeruleus Complex Distinguished by Expression of the Dorsal Neural Tube Marker Pax7
NW Plummer, EL Scappini, KG Smith… - Frontiers in …, 2017 - frontiersin.org
Central noradrenergic neurons, collectively defined by synthesis of the neurotransmitter
norepinephrine, are a diverse collection of cells in the hindbrain, differing in their anatomy …
norepinephrine, are a diverse collection of cells in the hindbrain, differing in their anatomy …