Macrolides such as azithromycin are commonly prescribed antibiotics during pregnancy.
The good oral bioavailability and transplacental transfer of azithromycin make this drug …

Background Azithromycin is an azalide antibiotic with an extensive range of indications and
has become a common treatment option due to its convenient dosing regimen and …

Background Initial randomised controlled trials (RCTs) showed that prophylactic
azithromycin in pregnant women improved maternal and neonatal outcomes; however, the …

Objective: The purpose of this study was to characterize the pharmacokinetics of orally
administered azithromycin in the term gravid woman. Study Design: Twenty women who …

Background Currently there are trials in Africa and Asia investigating whether prophylactic
azithromycin during pregnancy reduces infection-related neonatal morbidity and mortality …

METHODS: This was a double-blind, placebo-controlled randomized trial. Gambian women
in labor were given either an oral dose of azithromycin (2 g) or placebo. Follow-up was …

Background The use of azithromycin reduces maternal infection in women during
unplanned cesarean delivery, but its effect on those with planned vaginal delivery is …

Objectives A systematic review with met‐analysis was performed to summarise the evidence
on the effect of intrapartum azithromycin on maternal and neonatal infections and deaths …

Importance Neonatal sepsis is a leading cause of neonatal mortality. New interventions are
needed to decrease neonatal sepsis and mortality in regions with highest burden. Objective …

Background Neonatal deaths, estimated at approximately 4 million annually, now account
for almost 40% of global mortality in children aged under-five. Bacterial sepsis is a leading …