Discrete attractor dynamics underlies persistent activity in the frontal cortex

HK Inagaki, L Fontolan, S Romani, K Svoboda - Nature, 2019 - nature.com
Short-term memories link events separated in time, such as past sensation and future
actions. Short-term memories are correlated with slow neural dynamics, including selective …

Maintenance of persistent activity in a frontal thalamocortical loop

ZV Guo, HK Inagaki, K Daie, S Druckmann, CR Gerfen… - Nature, 2017 - nature.com
Persistent neural activity maintains information that connects past and future events. Models
of persistent activity often invoke reverberations within local cortical circuits, but long-range …

Robust neuronal dynamics in premotor cortex during motor planning

N Li, K Daie, K Svoboda, S Druckmann - Nature, 2016 - nature.com
Neural activity maintains representations that bridge past and future events, often over many
seconds. Network models can produce persistent and ramping activity, but the positive …

Emergence of cortical network motifs for short-term memory during learning

XW Chia, JK Tan, LF Ang, T Kamigaki… - Nature …, 2023 - nature.com
Learning of adaptive behaviors requires the refinement of coordinated activity across
multiple brain regions. However, how neural communications develop during learning …

Targeted photostimulation uncovers circuit motifs supporting short-term memory

K Daie, K Svoboda, S Druckmann - Nature neuroscience, 2021 - nature.com
Short-term memory is associated with persistent neural activity that is maintained by positive
feedback between neurons. To explore the neural circuit motifs that produce memory-related …

Attractor dynamics gate cortical information flow during decision-making

A Finkelstein, L Fontolan, MN Economo, N Li… - Nature …, 2021 - nature.com
Decisions are held in memory until enacted, which makes them potentially vulnerable to
distracting sensory input. Gating of information flow from sensory to motor areas could …

Recurrent circuit dynamics underlie persistent activity in the macaque frontoparietal network

E Hart, AC Huk - Elife, 2020 - elifesciences.org
During delayed oculomotor response tasks, neurons in the lateral intraparietal area (LIP)
and the frontal eye fields (FEF) exhibit persistent activity that reflects the active maintenance …

Emergence of reproducible spatiotemporal activity during motor learning

AJ Peters, SX Chen, T Komiyama - Nature, 2014 - nature.com
The motor cortex is capable of reliably driving complex movements, yet exhibits
considerable plasticity during motor learning,,,,,,,. These observations suggest that the …

Graded persistent activity in entorhinal cortex neurons

AV Egorov, BN Hamam, E Fransén, ME Hasselmo… - Nature, 2002 - nature.com
Working memory represents the ability of the brain to hold externally or internally driven
information for relatively short periods of time,. Persistent neuronal activity is the elementary …

Cortical pattern generation during dexterous movement is input-driven

BA Sauerbrei, JZ Guo, JD Cohen, M Mischiati, W Guo… - Nature, 2020 - nature.com
The motor cortex controls skilled arm movement by sending temporal patterns of activity to
lower motor centres. Local cortical dynamics are thought to shape these patterns throughout …