Cell death in the lung: the apoptosis–necroptosis axis

M Sauler, IS Bazan, PJ Lee - Annual review of physiology, 2019 - annualreviews.org
Regulated cell death is a major mechanism to eliminate damaged, infected, or superfluous
cells. Previously, apoptosis was thought to be the only regulated cell death mechanism; …

Apoptosis in lung injury and remodeling

X Li, R Shu, G Filippatos… - Journal of applied …, 2004 - journals.physiology.org
The mode of cell death termed apoptosis, sometimes referred to as programmed cell death,
is as critical a determinant of cell population size as is cell proliferation. Although best …

Apoptosis in lung pathophysiology

A Fine, Y Janssen-Heininger… - … of Physiology-Lung …, 2000 - journals.physiology.org
As recently as 1993, fewer than 10 manuscripts had been published on the topic of
apoptosis specifically in the lung. Although that number is increasing, far fewer papers …

Regulated necrosis in pulmonary disease. A focus on necroptosis and ferroptosis

S Minagawa, M Yoshida, J Araya, H Hara… - American Journal of …, 2020 - atsjournals.org
To date, increasing evidence suggests the possible involvement of various types of cell
death in lung diseases. The recognized regulated cell death includes necrotic cell death that …

Apoptosis in the lung: induction, clearance and detection

PM Henson, RM Tuder - American Journal of Physiology …, 2008 - journals.physiology.org
Apoptosis and other forms of programmed cell death are important contributors to lung
pathophysiology. In this brief review, we discuss some of the implications of finding apoptotic …

Acute lung injury and cell death: how many ways can cells die?

PS Tang, M Mura, R Seth, M Liu - American Journal of …, 2008 - journals.physiology.org
Apoptosis has been considered as an underlying mechanism in acute lung injury/acute
respiratory distress syndrome and multiorgan dysfunction syndrome. Recently, several …

Apoptosis and emphysema: the missing link

RM Tuder, I Petrache, JA Elias, NF Voelkel… - American journal of …, 2003 - atsjournals.org
Emphysema, which with chronic bronchitis accounts for model of emphysema initiated by
blockade of vascular endothelial growth factor (VEGF) receptors (8), Aoshiba most of the …

Lung infections: role of apoptosis in host defense and pathogenesis of disease

M Behnia, KA Robertson, WJ Martin II - Chest, 2000 - search.proquest.com
Apoptosis is a form of cell death that has gained enormous attention during the past few
years, and its mechanisms, important to biology and medicine, are being unraveled at an …

[PDF][PDF] Epithelial cell apoptosis and lung remodeling

K Kuwano - Cell Mol Immunol, 2007 - cmi.ustc.edu.cn
Lung epithelium is the primary site of lung damage in various lung diseases. Epithelial cell
apoptosis has been considered to be initial event in various lung diseases. Apoptosis …

Apoptosis in lung fibrosis and repair

BD Uhal - Chest, 2002 - Elsevier
Cell death by apoptosis has fundamental significance in both normal lung homeostasis and
a variety of pathologic processes, and for this reason apoptosis in the lung is a rapidly …