[HTML][HTML] In prostate cancer cells cytokines are early responders to gravitational changes occurring in parabolic flights

H Schulz, D Dietrichs, M Wehland, TJ Corydon… - International Journal of …, 2022 - mdpi.com
The high mortality in men with metastatic prostate cancer (PC) establishes the need for
diagnostic optimization by new biomarkers. Mindful of the effect of real microgravity on …

[HTML][HTML] Real microgravity influences the cytoskeleton and focal adhesions in human breast cancer cells

MZ Nassef, S Kopp, M Wehland, D Melnik… - International journal of …, 2019 - mdpi.com
With the increasing number of spaceflights, it is crucial to understand the changes occurring
in human cells exposed to real microgravity (r-µ g) conditions. We tested the effect of r-µ g on …

[HTML][HTML] Microgravity and space medicine

D Grimm - International Journal of Molecular Sciences, 2021 - mdpi.com
This Special Issue (SI),“Microgravity and Space Medicine”, covers research articles and
reviews focusing on gravitational biology, cancer research and space medicine. It includes …

[HTML][HTML] Short-term microgravity influences cell adhesion in human breast cancer cells

MZ Nassef, S Kopp, D Melnik, TJ Corydon… - International Journal of …, 2019 - mdpi.com
With the commercialization of spaceflight and the exploration of space, it is important to
understand the changes occurring in human cells exposed to real microgravity (r-µ g) …

Microgravity alters cancer growth and progression

DV Jhala, RK Kale, RP Singh - Current cancer drug targets, 2014 - ingentaconnect.com
Study of the process of cancer initiation, growth and progression in altered gravity is of
utmost importance considering the health status of researchers visiting in space and future …

[HTML][HTML] Microgravity affects thyroid cancer cells during the TEXUS-53 mission stronger than hypergravity

S Kopp, M Krüger, J Bauer, M Wehland… - International journal of …, 2018 - mdpi.com
Thyroid cancer is the most abundant tumor of the endocrine organs. Poorly differentiated
thyroid cancer is still difficult to treat. Human cells exposed to long-term real (r-) and …

[HTML][HTML] Microgravity modulates effects of chemotherapeutic drugs on cancer cell migration

D Prasanth, S Suresh, S Prathivadhi-Bhayankaram… - Life, 2020 - mdpi.com
Microgravity or the condition of apparent weightlessness causes bone, muscular and
immune system dysfunctions in astronauts following spaceflights. These organ and system …

Differential gene regulation under altered gravity conditions in follicular thyroid cancer cells: relationship between the extracellular matrix and the cytoskeleton

C Ulbrich, J Pietsch, J Grosse, M Wehland… - Cellular Physiology and …, 2011 - karger.com
Extracellular matrix proteins, adhesion molecules, and cytoskeletal proteins form a dynamic
network interacting with signalling molecules as an adaptive response to altered gravity. An …

[HTML][HTML] Simulated microgravity influences VEGF, MAPK, and PAM signaling in prostate cancer cells

TE Hybel, D Dietrichs, J Sahana, TJ Corydon… - International Journal of …, 2020 - mdpi.com
Prostate cancer is one of the leading causes of cancer mortality in men worldwide. An
unusual but unique environment for studying tumor cell processes is provided by …

[HTML][HTML] Simulated Microgravity-Induced Changes to Drug Response in Cancer Cells Quantified Using Fluorescence Morphometry

S McKinley, A Taylor, C Peeples, M Jacob, G Khaparde… - Life, 2023 - mdpi.com
Unlike plants that have special gravity-sensing cells, such special cells in animals are yet to
be discovered. However, microgravity, the condition of apparent weightlessness, causes …